Measurement of pre-existing IgG and IgM antibodies against polyethylene glycol in healthy individuals BM Chen, YC Su, CJ Chang, PA Burnouf, KH Chuang, CH Chen, ... Analytical chemistry 88 (21), 10661-10666, 2016 | 173 | 2016 |
An activity-based near-infrared glucuronide trapping probe for imaging β-glucuronidase expression in deep tissues TC Cheng, SR Roffler, SC Tzou, KH Chuang, YC Su, CH Chuang, ... Journal of the American Chemical Society 134 (6), 3103-3110, 2012 | 102 | 2012 |
Sensitive quantification of PEGylated compounds by second-generation anti-poly (ethylene glycol) monoclonal antibodies YC Su, BM Chen, KH Chuang, TL Cheng, SR Roffler Bioconjugate chemistry 21 (7), 1264-1270, 2010 | 97 | 2010 |
Tumor-targeting prodrug-activating bacteria for cancer therapy CM Cheng, YL Lu, KH Chuang, WC Hung, J Shiea, YC Su, CH Kao, ... Cancer gene therapy 15 (6), 393, 2008 | 91 | 2008 |
Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes YC Hsieh, HE Wang, WW Lin, SR Roffler, TC Cheng, YC Su, JJ Li, ... Theranostics 8 (11), 3164, 2018 | 88 | 2018 |
Premature Drug Release from Polyethylene Glycol (PEG)-Coated Liposomal Doxorubicin via Formation of the Membrane Attack Complex E Chen, BM Chen, YC Su, YC Chang, TL Cheng, Y Barenholz, SR Roffler ACS nano, 2020 | 81 | 2020 |
Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy YC Su, PA Burnouf, KH Chuang, BM Chen, TL Cheng, SR Roffler Nature Communications 8, 2017 | 65 | 2017 |
A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol CJ Chang, CH Chen, BM Chen, YC Su, YT Chen, MS Hershfield, ... Nature Communications 8 (1), 522, 2017 | 58 | 2017 |
Structural basis of polyethylene glycol recognition by antibody CC Lee, YC Su, TP Ko, LL Lin, CY Yang, SSC Chang, SR Roffler, ... Journal of biomedical science 27 (1), 1-13, 2020 | 43 | 2020 |
Gene expression imaging by enzymatic catalysis of a fluorescent probe via membrane-anchored [beta]-glucuronidase YC Su, KH Chuang, YM Wang, CM Cheng, SR Lin, JY Wang, JJ Hwang, ... Gene therapy 14 (7), 565, 2007 | 38 | 2007 |
Engineering chimeric receptors to investigate the size-and rigidity-dependent interaction of PEGylated nanoparticles with cells WC Huang, PA Burnouf, YC Su, BM Chen, KH Chuang, CW Lee, PK Wei, ... ACS nano 10 (1), 648-662, 2016 | 36 | 2016 |
Selective delivery of PEGylated compounds to tumor cells by anti-PEG hybrid antibodies HY Tung, YC Su, BM Chen, PA Burnouf, WC Huang, KH Chuang, YT Yan, ... Molecular cancer therapeutics 14 (6), 1317-1326, 2015 | 36 | 2015 |
The affinity of elongated Membrane-Tethered ligands Determines Potency of T cell receptor Triggering BM Chen, MA Al-Aghbar, CH Lee, TC Chang, YC Su, YC Li, SE Chang, ... Frontiers in Immunology 8, 2017 | 31 | 2017 |
Enhanced drug internalization and therapeutic efficacy of PEGylated nanoparticles by one-step formulation with anti-mPEG bispecific antibody in intrinsic drug-resistant breast … YA Cheng, IJ Chen, YC Su, KW Cheng, YC Lu, WW Lin, YC Hsieh, ... Biomaterials science 7 (8), 3404-3417, 2019 | 28 | 2019 |
Micro-PET imaging of β-glucuronidase activity by the hydrophobic conversion of a glucuronide probe SC Tzou, S Roffler, KH Chuang, HP Yeh, CH Kao, YC Su, CM Cheng, ... Radiology 252 (3), 754-762, 2009 | 27 | 2009 |
Development of a highly sensitive enzyme-linked immunosorbent assay (ELISA) through use of poly-protein G-expressing cell-based microplates YJ Chen, M Chen, YC Hsieh, YC Su, CH Wang, CM Cheng, AP Kao, ... Scientific reports 8 (1), 1-11, 2018 | 25 | 2018 |
PET imaging of β-glucuronidase activity by an activity-based 124I-trapping probe for the personalized glucuronide prodrug targeted therapy YC Su, TC Cheng, YL Leu, SR Roffler, JY Wang, CH Chuang, CH Kao, ... Molecular cancer therapeutics 13 (12), 2852-2863, 2014 | 24 | 2014 |
Sensitivity of PEGylated interferon detection by anti-polyethylene glycol (PEG) antibodies depends on PEG length TC Cheng, KH Chuang, M Chen, HE Wang, SC Tzou, YC Su, CH Chuang, ... Bioconjugate chemistry 24 (8), 1408-1413, 2013 | 18 | 2013 |
Reversible glycosidic switch for secure delivery of molecular nanocargos PA Burnouf, YL Leu, YC Su, K Wu, WC Lin, SR Roffler Nature communications 9 (1), 1-13, 2018 | 16 | 2018 |
Bispecific Antibody (HER2× mPEG) Enhances Anti-Cancer Effects by Precise Targeting and Accumulation of mPEGylated Liposomes IJ Chen, YA Cheng, KW Ho, WW Lin, KW Cheng, YC Lu, YC Hsieh, ... Acta Biomaterialia, 2020 | 15 | 2020 |