MYC as a regulator of ribosome biogenesis and protein synthesis J Van Riggelen, A Yetil, DW Felsher Nature Reviews Cancer 10 (4), 301-309, 2010 | 985 | 2010 |
Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation CH Wu, J Van Riggelen, A Yetil, AC Fan, P Bachireddy, DW Felsher Proceedings of the National Academy of Sciences 104 (32), 13028-13033, 2007 | 485 | 2007 |
Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch S Giuriato, S Ryeom, AC Fan, P Bachireddy, RC Lynch, MJ Rioth, ... Proceedings of the National Academy of Sciences 103 (44), 16266-16271, 2006 | 191 | 2006 |
MYC—master regulator of the cancer epigenome and transcriptome CJ Poole, J Van Riggelen Genes 8 (5), 142, 2017 | 149 | 2017 |
The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance J Van Riggelen, J Müller, T Otto, V Beuger, A Yetil, PS Choi, C Kosan, ... Genes & development 24 (12), 1281-1294, 2010 | 139 | 2010 |
High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation AR Wu, TLA Kawahara, NA Rapicavoli, J Van Riggelen, EH Shroff, L Xu, ... Lab on a Chip 12 (12), 2190-2198, 2012 | 82 | 2012 |
DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt’s lymphoma CJ Poole, W Zheng, A Lodh, A Yevtodiyenko, D Liefwalker, H Li, ... Oncotarget 8 (44), 76898, 2017 | 59 | 2017 |
Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation Y Cai, G Zhu, S Liu, Z Pan, M Quintero, CJ Poole, C Lu, H Zhu, B Islam, ... Cell Discovery 5 (1), 7, 2019 | 56 | 2019 |
Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction PS Choi, J Van Riggelen, AJ Gentles, P Bachireddy, K Rakhra, SJ Adam, ... Proceedings of the National Academy of Sciences 108 (42), 17432-17437, 2011 | 52 | 2011 |
Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells A Bachmann, B Hanke, R Zawatzky, U Soto, J Van Riggelen, ... Journal of virology 76 (1), 280-291, 2002 | 43 | 2002 |
MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy) methylation and gene expression to maintain a neoplastic phenotype in T-ALL CJ Poole, A Lodh, JH Choi, J Van Riggelen Epigenetics & chromatin 12, 1-20, 2019 | 36 | 2019 |
Myc and a Cdk2 senescence switch J Van Riggelen, DW Felsher Nature Cell Biology 12 (1), 7-9, 2010 | 35 | 2010 |
Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells J Van Riggelen, G Buchwalter, U Soto, JDC Arce, H Zur Hausen, ... Journal of Biological Chemistry 280 (5), 3286-3294, 2005 | 35 | 2005 |
p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia A Yetil, B Anchang, AM Gouw, SJ Adam, T Zabuawala, R Parameswaran, ... Oncotarget 6 (6), 3563, 2015 | 28 | 2015 |
Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity A Alptekin, B Ye, Y Yu, CJ Poole, J van Riggelen, Y Zha, HF Ding Oncogene 38 (50), 7504-7520, 2019 | 27 | 2019 |
Targeting the MYC oncogene in burkitt lymphoma through HSP90 inhibition CJ Poole, W Zheng, H Lee, D Young, A Lodh, A Chadli, J Van Riggelen Cancers 10 (11), 448, 2018 | 22 | 2018 |
FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome T Hu, Q Wu, Y Chong, H Qin, CJ Poole, J Van Riggelen, M Ren, ... Leukemia 32 (11), 2363-2373, 2018 | 22 | 2018 |
Ectopic expression of nonliganded retinoic acid receptor β abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells JDC Arce, U Soto, J Van Riggelen, E Schwarz, H Zur Hausen, F Rösl Journal of Biological Chemistry 279 (44), 45408-45416, 2004 | 17 | 2004 |
TGFβ-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas J Müller, B Samans, J Van Riggelen, G Fagà, R Peh KN, CL Wei, H Müller, ... Cell Cycle 9 (23), 4622-4626, 2010 | 9 | 2010 |
Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells MY Liu, JD Klement, CJ Langan, J van Riggelen, K Liu Cellular immunology 366, 104397, 2021 | 7 | 2021 |