In Vivo Mapping of Eukaryotic RNA Interactomes Reveals Principles of Higher-Order Organization and Regulation YW Jong Ghut Ashley Aw, Yang Shen, Andreas Wilm, Miao Sun, Xin Ni Lim, Kum ... Molecular Cell 62 (4), 603-617, 2016 | 338 | 2016 |
Salt dependence of the radius of gyration and flexibility of single-stranded DNA in solution probed by small-angle x-ray scattering AYL Sim, J Lipfert, D Herschlag, S Doniach Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 86 (2 …, 2012 | 182 | 2012 |
Structure mapping of dengue and Zika viruses reveals functional long-range interactions RG Huber, XN Lim, WC Ng, AYL Sim, HX Poh, Y Shen, SY Lim, ... Nature communications 10 (1), 1408, 2019 | 125 | 2019 |
Dynamic charge interactions create surprising rigidity in the ER/K α-helical protein motif S Sivaramakrishnan, BJ Spink, AYL Sim, S Doniach, JA Spudich Proceedings of the National Academy of Sciences 105 (36), 13356-13361, 2008 | 125 | 2008 |
Modeling nucleic acids AYL Sim, P Minary, M Levitt Current opinion in structural biology 22 (3), 273-278, 2012 | 117 | 2012 |
Fully differentiable coarse-grained and all-atom knowledge-based potentials for RNA structure evaluation J Bernauer, X Huang, AYL Sim, M Levitt Rna 17 (6), 1066-1075, 2011 | 110 | 2011 |
Mixing and matching detergents for membrane protein NMR structure determination L Columbus, J Lipfert, K Jambunathan, DA Fox, AYL Sim, S Doniach, ... Biophysical Journal 96 (3), 195a, 2009 | 109 | 2009 |
Dissecting electrostatic screening, specific ion binding, and ligand binding in an energetic model for glycine riboswitch folding J Lipfert, AYL Sim, D Herschlag, S Doniach Rna 16 (4), 708-719, 2010 | 67 | 2010 |
Modeling and design by hierarchical natural moves AYL Sim, M Levitt, P Minary Proceedings of the National Academy of Sciences 109 (8), 2890-2895, 2012 | 55 | 2012 |
Mechanism of enhanced immature dengue virus attachment to endosomal membrane induced by prM antibody M Wirawan, G Fibriansah, JK Marzinek, XX Lim, TS Ng, AYL Sim, ... Structure 27 (2), 253-267. e8, 2019 | 48 | 2019 |
Electrostatics of nucleic acid folding under conformational constraint PC Anthony, AYL Sim, VB Chu, S Doniach, SM Block, D Herschlag Journal of the American Chemical Society 134 (10), 4607-4614, 2012 | 39 | 2012 |
Photoluminescence of hydrothermally epitaxied ZnO films AYL Sim, GKL Goh, S Tripathy, D Andeen, FF Lange Electrochimica acta 52 (8), 2933-2937, 2007 | 39 | 2007 |
In vitro selection of mutant HDM2 resistant to Nutlin inhibition SJ Wei, T Joseph, AYL Sim, L Yurlova, K Zolghadr, D Lane, C Verma, ... PloS one 8 (4), e62564, 2013 | 37 | 2013 |
R248Q mutation—Beyond p53‐DNA binding JWK Ng, D Lama, S Lukman, DP Lane, CS Verma, AYL Sim Proteins: Structure, Function, and Bioinformatics 83 (12), 2240-2250, 2015 | 32 | 2015 |
Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches HYK Kaan, AYL Sim, SKJ Tan, C Verma, H Song PLoS One 12 (6), e0178381, 2017 | 31 | 2017 |
Clustering to identify RNA conformations constrained by secondary structure AYL Sim, M Levitt Proceedings of the National Academy of Sciences 108 (9), 3590-3595, 2011 | 29 | 2011 |
Mechanism of stapled peptide binding to MDM2: possible consequences for peptide design AYL Sim, T Joseph, DP Lane, C Verma Journal of Chemical Theory and Computation 10 (4), 1753-1761, 2014 | 20 | 2014 |
The role of gelsolin domain 3 in familial amyloidosis (Finnish type) H Zorgati, M Larsson, W Ren, AYL Sim, J Gettemans, JM Grimes, W Li, ... Proceedings of the National Academy of Sciences 116 (28), 13958-13963, 2019 | 18 | 2019 |
Topology independent comparison of RNA 3D structures using the CLICK algorithm MN Nguyen, AYL Sim, Y Wan, MS Madhusudhan, C Verma Nucleic acids research 45 (1), e5-e5, 2017 | 17 | 2017 |
NEAR trial: A single-arm phase II trial of neoadjuvant apalutamide monotherapy and radical prostatectomy in intermediate-and high-risk prostate cancer LS Lee, AYL Sim, CW Ong, X Yang, CCY Ng, W Liu, V Rajasegaran, ... Prostate Cancer and Prostatic Diseases 25 (4), 741-748, 2022 | 16 | 2022 |