| Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells YH Cheng, YC Chen, E Lin, R Brien, S Jung, YT Chen, W Lee, Z Hao, ... Nature communications 10 (1), 2163, 2019 | 195 | 2019 |
| Scaling and automation of a high-throughput single-cell-derived tumor sphere assay chip YH Cheng, YC Chen, R Brien, E Yoon Lab on a Chip 16 (19), 3708-3717, 2016 | 63 | 2016 |
| Paired single cell co-culture microenvironments isolated by two-phase flow with continuous nutrient renewal YC Chen, YH Cheng, HS Kim, PN Ingram, JE Nor, E Yoon Lab on a Chip 14 (16), 2941-2947, 2014 | 60 | 2014 |
| Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer YC Chen, ME Gonzalez, B Burman, X Zhao, T Anwar, M Tran, N Medhora, ... Cell reports 27 (13), 3916-3926. e5, 2019 | 58 | 2019 |
| Plasminogen activator inhibitor 1 (PAI1) promotes actin cytoskeleton reorganization and glycolytic metabolism in triple-negative breast cancer BA Humphries, JM Buschhaus, YC Chen, HR Haley, T Qyli, B Chiang, ... Molecular Cancer Research 17 (5), 1142-1154, 2019 | 55 | 2019 |
| Single-cell RNA-sequencing of migratory breast cancer cells: discovering genes associated with cancer metastasis YC Chen, S Sahoo, R Brien, S Jung, B Humphries, W Lee, YH Cheng, ... Analyst 144 (24), 7296-7309, 2019 | 54 | 2019 |
| Macrophages enhance migration in inflammatory breast cancer cells via RhoC GTPase signaling SG Allen, YC Chen, JM Madden, CL Fournier, MA Altemus, AB Hiziroglu, ... Scientific reports 6 (1), 39190, 2016 | 47 | 2016 |
| Functional isolation of tumor-initiating cells using microfluidic-based migration identifies phosphatidylserine decarboxylase as a key regulator YC Chen, B Humphries, R Brien, AE Gibbons, YT Chen, T Qyli, HR Haley, ... Scientific reports 8 (1), 244, 2018 | 37 | 2018 |
| Microfluidics 3D gel-island chip for single cell isolation and lineage-dependent drug responses study Z Zhang, YC Chen, YH Cheng, Y Luan, E Yoon Lab on a Chip 16 (13), 2504-2512, 2016 | 26 | 2016 |
| Selective photomechanical detachment and retrieval of divided sister cells from enclosed microfluidics for downstream analyses YC Chen, HW Baac, KT Lee, S Fouladdel, K Teichert, JG Ok, YH Cheng, ... ACS nano 11 (5), 4660-4668, 2017 | 23 | 2017 |
| Single cell proteolytic assays to investigate cancer clonal heterogeneity and cell dynamics using an efficient cell loading scheme YC Chen, YH Cheng, P Ingram, E Yoon Scientific reports 6 (1), 27154, 2016 | 13 | 2016 |
| Osmotically actuated micropumps and control valves for point-of-care applications YC Chen, TH Kang, PN Ingram, YH Cheng, E Yoon Journal of Microelectromechanical Systems 24 (4), 982-989, 2014 | 7 | 2014 |
| Systems and methods for whole cell analysis E Yoon, Y Cheng, YC Chen, R Brien, MS Wicha US Patent 11,426,729, 2022 | 3 | 2022 |
| Cell-niche-on-chip: Paired single cell co-culture platforms using immiscible liquid isolation and semi-permeable membranes YC Chen, YH Cheng, E Yoon 2014 IEEE 27th International Conference on Micro Electro Mechanical Systems …, 2014 | 1 | 2014 |
| Microfluidic high-throughput cell pairing and retrieval for studying breast cancer-MSC engulfment YC Chen, ME Gonzalez, AB Hiziroglu, X Zhao, R Brien, YH Cheng, ... 21st International Conference on Miniaturized Systems for Chemistry and Life …, 2020 | | 2020 |
| High-Efficiency Microfluidics for Single Cell Phenotypic and Transcriptomic Analysis of Rare Cancer Cells YH Cheng | | 2018 |
| Single-cell RNA-sequencing of migratory cancer cells sorted by microfluidics: Discovering drivers of cancer metastasis YC Chen, R Brien, S Sahoo, W Lee, YH Cheng, S Jung, H Haley, K Luker, ... 22nd International Conference on Miniaturized Systems for Chemistry and Life …, 2018 | | 2018 |
| Microfluidic vertical adhesion-suspension co-culture platform for studying cancer stem cell-fibroblast interactions YC Chen, Z Zhang, YH Cheng, E Yoon, MS Wicha Cancer Research 77 (13_Supplement), 5909-5909, 2017 | | 2017 |
| A 12,800-well single-cell-derived sphere assay chip utilizing highly-parallel microfluidic structures for cancer heterogeneity studies YH Cheng, YC Chen, R Brien, E Yoon 20th International Conference on Miniaturized Systems for Chemistry and Life …, 2016 | | 2016 |
| Single-cell transcriptome analysis to study tumor-stromal interaction on cancer-stem-cells using vertical adhesion-suspension co-culture platforms YC Chen, Z Zhang, YH Cheng, E Yoon 20th International Conference on Miniaturized Systems for Chemistry and Life …, 2016 | | 2016 |
