| Caught up in a Wnt storm: Wnt signaling in cancer RH Giles, JH Van Es, H Clevers Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1653 (1), 1-24, 2003 | 1938 | 2003 |
| Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP F Petrif, RH Giles, HG Dauwerse, JJ Saris, R Hennekam, M Masuno, ... Nature 376 (6538), 348-351, 1995 | 1413 | 1995 |
| Mutations in the APC tumour suppressor gene cause chromosomal instability R Fodde, J Kuipers, C Rosenberg, R Smits, M Kielman, C Gaspar, ... Nature cell biology 3 (4), 433-438, 2001 | 914 | 2001 |
| European association of urology guidelines on renal cell carcinoma: the 2019 update B Ljungberg, L Albiges, Y Abu-Ghanem, K Bensalah, S Dabestani, ... European urology 75 (5), 799-810, 2019 | 897 | 2019 |
| Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways L Sang, JJ Miller, KC Corbit, RH Giles, MJ Brauer, EA Otto, LM Baye, ... Cell 145 (4), 513-528, 2011 | 572 | 2011 |
| Conjunction dysfunction: CBP/p300 in human disease RH Giles, DJM Peters, MH Breuning Trends in Genetics 14 (5), 178-183, 1998 | 533 | 1998 |
| Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling M Chaki, R Airik, AK Ghosh, RH Giles, R Chen, GG Slaats, H Wang, ... Cell 150 (3), 533-548, 2012 | 361 | 2012 |
| Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy EA Otto, TW Hurd, R Airik, M Chaki, W Zhou, C Stoetzel, SB Patil, S Levy, ... Nature genetics 42 (10), 840-850, 2010 | 351 | 2010 |
| Genetic analysis of von Hippel‐Lindau disease M Nordstrom‐O'Brien, RB van der Luijt, E van Rooijen, ... Human mutation 31 (5), 521-537, 2010 | 297 | 2010 |
| Genetic, environmental, and epigenetic factors involved in CAKUT N Nicolaou, KY Renkema, EMHF Bongers, RH Giles, NVAM Knoers Nature Reviews Nephrology 11 (12), 720-731, 2015 | 235 | 2015 |
| FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair W Zhou, EA Otto, A Cluckey, R Airik, TW Hurd, M Chaki, K Diaz, FP Lach, ... Nature genetics 44 (8), 910-915, 2012 | 227 | 2012 |
| Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease A van Koppen, JA Joles, BWM van Balkom, SK Lim, D de Kleijn, RH Giles, ... PloS one 7 (6), e38746, 2012 | 209 | 2012 |
| Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis SG Basten, RH Giles Cilia 2 (1), 1-23, 2013 | 197 | 2013 |
| An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes G Wheway, M Schmidts, DA Mans, K Szymanska, TMT Nguyen, H Racher, ... Nature cell biology 17 (8), 1074-1087, 2015 | 195 | 2015 |
| Updated European Association of Urology Guidelines: recommendations for the treatment of first-line metastatic clear cell renal cancer T Powles, L Albiges, M Staehler, K Bensalah, S Dabestani, RH Giles, ... European urology 73 (3), 311-315, 2018 | 189 | 2018 |
| An organelle-specific protein landscape identifies novel diseases and molecular mechanisms K Boldt, J Van Reeuwijk, Q Lu, K Koutroumpas, TMT Nguyen, Y Texier, ... Nature communications 7 (1), 1-13, 2016 | 188 | 2016 |
| The many faces of the tumor suppressor gene APC JH van Es, RH Giles, HC Clevers Experimental cell research 264 (1), 126-134, 2001 | 182 | 2001 |
| EAU guidelines on renal cell carcinoma B Ljungberg, L Albiges, K Bensalah, A Bex, RH Giles, M Hora, MA Kuczyk, ... European Association of Urology, 2020 | 168 | 2020 |
| Updated European Association of Urology guidelines on renal cell carcinoma: immune checkpoint inhibition is the new backbone in first-line treatment of metastatic clear-cell … L Albiges, T Powles, M Staehler, K Bensalah, RH Giles, M Hora, ... European urology 76 (2), 151-156, 2019 | 164 | 2019 |
| Diagnostic analysis of the Rubinstein-Taybi syndrome: five cosmids should be used for microdeletion detection and low number of protein truncating mutations F Petrij, HG Dauwerse, RI Blough, RH Giles, JJ van der Smagt, ... Journal of medical genetics 37 (3), 168-176, 2000 | 144 | 2000 |
Gertjan van OmmenProfessor in Human Genetics, Leiden University Medical CentreVerified email at lumc.nl
