| Design, synthesis and antitumor evaluation of phenyl N-mustard-quinazoline conjugates B Marvania, PC Lee, R Chaniyara, H Dong, S Suman, R Kakadiya, ... Bioorganic & medicinal chemistry 19 (6), 1987-1998, 2011 | 118 | 2011 |
| Lipoteichoic acid-induced nitric oxide synthase expression in RAW 264.7 macrophages is mediated by cyclooxygenase-2, prostaglandin E2, protein kinase A, p38 MAPK, and nuclear … YC Chang, PC Li, BC Chen, MS Chang, JL Wang, WT Chiu, CH Lin Cellular signalling 18 (8), 1235-1243, 2006 | 107 | 2006 |
| Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers TH Huang, L Huo, YN Wang, W Xia, Y Wei, SS Chang, WC Chang, ... Cancer cell 23 (6), 796-810, 2013 | 68 | 2013 |
| Targeting PKCδ as a therapeutic strategy against heterogeneous mechanisms of EGFR inhibitor resistance in EGFR-mutant lung cancer PC Lee, YF Fang, H Yamaguchi, WJ Wang, TC Chen, X Hong, B Ke, ... Cancer cell 34 (6), 954-969. e4, 2018 | 65 | 2018 |
| Potent antitumor bifunctional DNA alkylating agents, synthesis and biological activities of 3a-aza-cyclopenta [a] indenes R Kakadiya, H Dong, PC Lee, N Kapuriya, X Zhang, TC Chou, TC Lee, ... Bioorganic & medicinal chemistry 17 (15), 5614-5626, 2009 | 63 | 2009 |
| Oncogenic functions of Gli1 in pancreatic adenocarcinoma are supported by its PRMT1-mediated methylation Y Wang, JM Hsu, Y Kang, Y Wei, PC Lee, SJ Chang, YH Hsu, JL Hsu, ... Cancer research 76 (23), 7049-7058, 2016 | 52 | 2016 |
| Combination of bifunctional alkylating agent and arsenic trioxide synergistically suppresses the growth of drug-resistant tumor cells PC Lee, R Kakadiya, TL Su, TC Lee Neoplasia 12 (5), 376-IN2, 2010 | 47 | 2010 |
| Synthesis and antitumor evaluation of novel benzo [d] pyrrolo [2, 1-b] thiazole derivatives R Chaniyara, S Tala, CW Chen, PC Lee, R Kakadiya, H Dong, ... European journal of medicinal chemistry 53, 28-40, 2012 | 42 | 2012 |
| Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents N Kapuriya, R Kakadiya, H Dong, A Kumar, PC Lee, X Zhang, TC Chou, ... Bioorganic & medicinal chemistry 19 (1), 471-485, 2011 | 41 | 2011 |
| Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancer YY Chu, C Yam, MK Chen, LC Chan, M Xiao, YK Wei, H Yamaguchi, ... American Journal of Cancer Research 10 (2), 648, 2020 | 38 | 2020 |
| Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activity PC Lee, HJ Lee, R Kakadiya, K Sanjiv, TL Su, TC Lee Oncogene 32 (9), 1144-1154, 2013 | 32 | 2013 |
| Inhibition of c-MET upregulates PD-L1 expression in lung adenocarcinoma X Sun, CW Li, WJ Wang, MK Chen, H Li, YJ Lai, JL Hsu, PB Koller, ... American Journal of Cancer Research 10 (2), 564, 2020 | 23 | 2020 |
| The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer CW Chou, RY Yang, LC Chan, CF Li, L Sun, HH Lee, PC Lee, YP Sher, ... American journal of cancer research 10 (8), 2621, 2020 | 22 | 2020 |
| Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression CC Lin, YK Huang, CF Cho, YS Lin, CC Lo, TT Kuo, GC Tseng, ... Theranostics 10 (24), 10925, 2020 | 21 | 2020 |
| Novel bifunctional alkylating agents, 5, 10-dihydropyrrolo [1, 2-b] isoquinoline derivatives, synthesis and biological activity R Chaniyara, N Kapuriya, H Dong, PC Lee, S Suman, B Marvania, ... Bioorganic & medicinal chemistry 19 (1), 275-286, 2011 | 21 | 2011 |
| Enhanced suppression of tumor growth by concomitant treatment of human lung cancer cells with suberoylanilide hydroxamic acid and arsenic trioxide CW Chien, JH Yao, SY Chang, PC Lee, TC Lee Toxicology and applied pharmacology 257 (1), 59-66, 2011 | 19 | 2011 |
| Synthesis and characterization of the ethylene-carbonate-linked l-valine derivatives of 4, 4-dimethylcurcumin with potential anticancer activities DY Lee, HY Lin, M Ramasamy, SC Kuo, PC Lee, MT Hsieh Molecules 26 (22), 7050, 2021 | 6 | 2021 |
| Highly mimetic ex vivo lung‐cancer spheroid‐based physiological model for clinical precision therapeutics MY Shie, HY Fang, KW Kan, CC Ho, CY Tu, PC Lee, PR Hsueh, CH Chen, ... Advanced Science 10 (16), 2206603, 2023 | 5 | 2023 |
| EGFR potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers TH Huang, L Huo, YN Wang, W Xia, Y Wei, SS Chang, WC Chang, ... Cancer cell 23 (6), 796, 2013 | 3 | 2013 |
| Diarylheptanoid 35d overcomes EGFR TKI resistance by inducing hsp70-mediated lysosomal degradation of EGFR in EGFR-mutant lung adenocarcinoma X Hong, MT Hsieh, TY Tseng, HY Lin, HC Chang, T Yau, WC Cheng, B Ke, ... Journal of Biological Chemistry 299 (6), 2023 | 2 | 2023 |
