| mTOR controls mitochondrial dynamics and cell survival via MTFP1 M Morita, J Prudent, K Basu, V Goyon, S Katsumura, L Hulea, D Pearl, ... Molecular cell 67 (6), 922-935. e5, 2017 | 321 | 2017 |
| PGC-1α promotes breast cancer metastasis and confers bioenergetic flexibility against metabolic drugs S Andrzejewski, E Klimcakova, RM Johnson, S Tabariès, MG Annis, ... Cell metabolism 26 (5), 778-787. e5, 2017 | 246 | 2017 |
| PGC-1α supports glutamine metabolism in breast cancer S McGuirk, SP Gravel, G Deblois, DJ Papadopoli, B Faubert, A Wegner, ... Cancer & metabolism 1, 1-11, 2013 | 177 | 2013 |
| Metabolic fitness and plasticity in cancer progression S McGuirk, Y Audet-Delage, J St-Pierre Trends in cancer 6 (1), 49-61, 2020 | 104 | 2020 |
| Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1α AS Arnold, J Gill, M Christe, R Ruiz, S McGuirk, J St-Pierre, L Tabares, ... Nature communications 5 (1), 3569, 2014 | 94 | 2014 |
| Androgen-dependent repression of ERRγ reprograms metabolism in prostate cancer É Audet-Walsh, T Yee, S McGuirk, M Vernier, C Ouellet, J St-Pierre, ... Cancer research 77 (2), 378-389, 2017 | 86 | 2017 |
| Estrogen-related receptors are targetable ROS sensors M Vernier, CR Dufour, S McGuirk, C Scholtes, X Li, G Bourmeau, ... Genes & Development 34 (7-8), 544-559, 2020 | 83 | 2020 |
| PGC-1α Promotes the Growth of ErbB2/Neu–Induced Mammary Tumors by Regulating Nutrient Supply E Klimcakova, V Chénard, S McGuirk, D Germain, D Avizonis, WJ Muller, ... Cancer research 72 (6), 1538-1546, 2012 | 67 | 2012 |
| Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer S McGuirk, Y Audet-Delage, MG Annis, Y Xue, M Vernier, K Zhao, ... Elife 10, e65150, 2021 | 40 | 2021 |
| Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4 M Vernier, S McGuirk, CR Dufour, L Wan, E Audet-Walsh, J St-Pierre, ... Oncogene 39 (41), 6406-6420, 2020 | 35 | 2020 |
| Peroxisome proliferator‐activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal … JF Gill, J Delezie, G Santos, S McGuirk, S Schnyder, S Frank, M Rausch, ... Aging Cell 18 (5), e12993, 2019 | 25 | 2019 |
| Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production DA Patten, S McGuirk, U Anilkumar, G Antoun, K Gandhi, G Parmar, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (1), 118854, 2021 | 18 | 2021 |
| Interplay between ShcA signaling and PGC-1α triggers targetable metabolic vulnerabilities in breast cancer YK Im, O Najyb, SP Gravel, S McGuirk, R Ahn, DZ Avizonis, V Chénard, ... Cancer Research 78 (17), 4826-4838, 2018 | 15 | 2018 |
| HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin M Biondini, A Kiepas, L El-Houjeiri, MG Annis, BE Hsu, AM Fortier, ... Oncogene 41 (12), 1701-1717, 2022 | 14 | 2022 |
| PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation SP Gravel, YB Khalifa, S McGuirk, C St-Louis, KM Laurin, É Lavallée, ... Iscience 26 (4), 2023 | 6 | 2023 |
| Spatiotemporal modeling of chemoresistance evolution in breast tumors uncovers dependencies on SLC38A7 and SLC46A1 Y Audet-Delage, C St-Louis, L Minarrieta, S McGuirk, I Kurreal, MG Annis, ... Cell Reports 42 (10), 2023 | 3 | 2023 |
| The Frontiers of DNA Regulation: Developing a National Policy Framework Encouraging Transparency, Security, and Cost-efficiency of Genetic Technology and Data S McGuirk, S Sultmanis, AR Westwood, W Kathlyn N, N Nabavi Journal of Science Policy & Governance 16 (01), 2020 | | 2020 |
| PGC-1α regulates mitochondrial-sarcoplasmic reticulum (SR)-mediated calcium exchange, SR stress and cell death to mitigate skeletal muscle aging J Gill, J Delezie, S McGuirk, S Schnyder, S Gesa, S Frank, M Rausch, ... Aging cell, 2019 | | 2019 |
| PGC-1α regulates mitochondrial calcium homeostasis, SR stress and cell death to mitigate skeletal muscle aging JF Gill, J Delezie, G Santos, S McGuirk, S Schnyder, S Frank, M Rausch, ... bioRxiv, 451229, 2018 | | 2018 |
| Student perspective of STEM education in Canada C Cavanagh, L Crapper, K Dietrich, T Gruosso, C Gualtieri, YS Huang, ... https://www.sp-exchange.ca/reports, 2016 | | 2016 |
Vincent GiguereProfessor, McGill UniversityVerified email at mcgill.ca
