| RNA-programmed genome editing in human cells M Jinek, A East, A Cheng, S Lin, E Ma, J Doudna elife 2, e00471, 2013 | 2134 | 2013 |
| High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity V Pattanayak, S Lin, JP Guilinger, E Ma, JA Doudna, DR Liu Nature biotechnology 31 (9), 839-843, 2013 | 1448 | 2013 |
| Structures of Cas9 endonucleases reveal RNA-mediated conformational activation M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ... Science 343 (6176), 2014 | 1036 | 2014 |
| Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery S Lin, BT Staahl, RK Alla, JA Doudna elife 3, e04766, 2014 | 938 | 2014 |
| Generation of knock-in primary human T cells using Cas9 ribonucleoproteins K Schumann, S Lin, E Boyer, DR Simeonov, M Subramaniam, RE Gate, ... Proceedings of the National Academy of Sciences 112 (33), 10437-10442, 2015 | 580 | 2015 |
| Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions TW Lo, CS Pickle, S Lin, EJ Ralston, M Gurling, CM Schartner, Q Bian, ... Genetics 195 (2), 331-348, 2013 | 175 | 2013 |
| Biotin synthesis begins by hijacking the fatty acid synthetic pathway S Lin, RE Hanson, JE Cronan Nature chemical biology 6 (9), 682-688, 2010 | 172 | 2010 |
| Closing in on complete pathways of biotin biosynthesis S Lin, JE Cronan Molecular BioSystems 7 (6), 1811-1821, 2011 | 138 | 2011 |
| Escherichia coli O86 O-Antigen Biosynthetic Gene Cluster and Stepwise Enzymatic Synthesis of Human Blood Group B Antigen Tetrasaccharide W Yi, J Shao, L Zhu, M Li, M Singh, Y Lu, S Lin, H Li, K Ryu, J Shen, ... Journal of the American Chemical Society 127 (7), 2040-2041, 2005 | 102 | 2005 |
| Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis V Agarwal, S Lin, T Lukk, SK Nair, JE Cronan Proceedings of the National Academy of Sciences 109 (43), 17406-17411, 2012 | 89 | 2012 |
| The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis S Lin, JE Cronan Journal of Biological Chemistry 287 (44), 37010-37020, 2012 | 54 | 2012 |
| The wbnH gene of Escherichia coli O86: H2 encodes an α-1, 3-N-acetylgalactosaminyl transferase involved in the O-repeating unit biosynthesis W Yi, Q Yao, Y Zhang, E Motari, S Lin, PG Wang Biochemical and biophysical research communications 344 (2), 631-639, 2006 | 39 | 2006 |
| Synthesis of the α, ω-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway JE Cronan, S Lin Current opinion in chemical biology 15 (3), 407-413, 2011 | 38 | 2011 |
| TIM-mediated inhibition of HIV-1 release is antagonized by Nef but potentiated by SERINC proteins M Li, AA Waheed, J Yu, C Zeng, HY Chen, YM Zheng, A Feizpour, ... Proceedings of the National Academy of Sciences 116 (12), 5705-5714, 2019 | 28 | 2019 |
| Biosynthesis of complex indole alkaloids: elucidation of the concise pathway of okaramines CY Lai, IW Lo, RT Hewage, YC Chen, CT Chen, CF Lee, S Lin, MC Tang, ... Angewandte Chemie International Edition 56 (32), 9478-9482, 2017 | 26 | 2017 |
| Heritable genome editing using TALENs and CRISPR/Cas9 to engineer precise insertions and deletions in evolutionarily diverse nematode species TW Lo, CS Pickle, S Lin, EJ Ralston, M Gurling, CM Schartner, Q Bian, ... Genetics 195 (2), 331-348, 2013 | 17 | 2013 |
| Enhanced NK-92 cytotoxicity by CRISPR genome engineering using Cas9 ribonucleoproteins RS Huang, HA Shih, MC Lai, YJ Chang, S Lin Frontiers in immunology 11, 1008, 2020 | 15 | 2020 |
| Humanized COVID‐19 decoy antibody effectively blocks viral entry and prevents SARS‐CoV‐2 infection KY Huang, MS Lin, TC Kuo, CL Chen, CC Lin, YC Chou, TL Chao, ... EMBO molecular medicine 13 (1), e12828, 2021 | 13 | 2021 |
| RNA-programmed genome editing in human cells. elife 2: e00471 M Jinek, A East, A Cheng, S Lin, E Ma, J Doudna | 11 | 2013 |
| Evolution of a new function in an esterase: simple amino acid substitutions enable the activity present in the larger paralog, BioH H Flores, S Lin, G Contreras-Ferrat, JE Cronan, E Morett Protein Engineering, Design & Selection 25 (8), 387-395, 2012 | 8 | 2012 |
