Clarence Yapp
Clarence Yapp
Harvard Medical School, University of Oxford
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Cited by
Cited by
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah, S Santagata, PK Sorger
Elife 7, 2018
Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains
DA Hay, O Fedorov, S Martin, DC Singleton, C Tallant, C Wells, S Picaud, ...
Journal of the American Chemical Society 136 (26), 9308-9319, 2014
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia TherapySelective Inhibitor for CBP/p300 Bromodomains
S Picaud, O Fedorov, A Thanasopoulou, K Leonards, K Jones, J Meier, ...
Cancer research 75 (23), 5106-5119, 2015
Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues
SK Saka, Y Wang, JY Kishi, A Zhu, Y Zeng, W Xie, K Kirli, C Yapp, ...
Nature biotechnology 37 (9), 1080-1090, 2019
Inflammation activation and resolution in human tendon disease
SG Dakin, FO Martinez, C Yapp, G Wells, U Oppermann, BJF Dean, ...
Science translational medicine 7 (311), 311ra173-311ra173, 2015
5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ...
Chemical science 4 (8), 3110-3117, 2013
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ...
Journal of medicinal chemistry 57 (1), 42-55, 2014
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ...
Nature communications 11 (1), 1-13, 2020
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
A Kawamura, M Münzel, T Kojima, C Yapp, B Bhushan, Y Goto, A Tumber, ...
Nature communications 8 (1), 1-10, 2017
[1,2,4]Triazolo[4,3-a]phthalazines: Inhibitors of Diverse Bromodomains
O Fedorov, H Lingard, C Wells, OP Monteiro, S Picaud, T Keates, C Yapp, ...
Journal of medicinal chemistry 57 (2), 462-476, 2014
Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching
M Philpott, CM Rogers, C Yapp, C Wells, JP Lambert, C Strain-Damerell, ...
Epigenetics & chromatin 7 (1), 1-12, 2014
Potent and selective KDM5 inhibitor stops cellular demethylation of H3K4me3 at transcription start sites and proliferation of MM1S myeloma cells
A Tumber, A Nuzzi, ES Hookway, SB Hatch, S Velupillai, C Johansson, ...
Cell chemical biology 24 (3), 371-380, 2017
HSF1 phase transition mediates stress adaptation and cell fate decisions
G Gaglia, R Rashid, C Yapp, GN Joshi, CG Li, SL Lindquist, KA Sarosiek, ...
Nature cell biology 22 (2), 151-158, 2020
The response of tenocytes to commercial scaffolds used for rotator cuff repair.
RD Smith, A Carr, SG Dakin, SJ Snelling, C Yapp, O Hakimi
eCells and Materials Journal 30, 2016
The mechanical, structural, and compositional changes of tendon exposed to elastase
TM Grant, C Yapp, Q Chen, JT Czernuszka, MS Thompson
Annals of biomedical engineering 43 (10), 2477-2486, 2015
Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting …
CL Sutherell, C Tallant, OP Monteiro, C Yapp, JE Fuchs, O Fedorov, ...
Journal of medicinal chemistry 59 (10), 5095-5101, 2016
Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases
CC Thinnes, A Tumber, C Yapp, G Scozzafava, T Yeh, MC Chan, TA Tran, ...
Chemical Communications 51 (84), 15458-15461, 2015
Assessing histone demethylase inhibitors in cells: lessons learned
SB Hatch, C Yapp, RC Montenegro, P Savitsky, V Gamble, A Tumber, ...
Epigenetics & chromatin 10 (1), 1-17, 2017
Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer
R Rashid, G Gaglia, YA Chen, JR Lin, Z Du, Z Maliga, D Schapiro, C Yapp, ...
Scientific data 6 (1), 1-10, 2019
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Articles 1–20