| Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah, S Santagata, PK Sorger Elife 7, 2018 | 294 | 2018 |
| Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains DA Hay, O Fedorov, S Martin, DC Singleton, C Tallant, C Wells, S Picaud, ... Journal of the American Chemical Society 136 (26), 9308-9319, 2014 | 265 | 2014 |
| The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 200 | 2020 |
| Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia TherapySelective Inhibitor for CBP/p300 Bromodomains S Picaud, O Fedorov, A Thanasopoulou, K Leonards, K Jones, J Meier, ... Cancer research 75 (23), 5106-5119, 2015 | 193 | 2015 |
| Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues SK Saka, Y Wang, JY Kishi, A Zhu, Y Zeng, W Xie, K Kirli, C Yapp, ... Nature biotechnology 37 (9), 1080-1090, 2019 | 188 | 2019 |
| Inflammation activation and resolution in human tendon disease SG Dakin, FO Martinez, C Yapp, G Wells, U Oppermann, BJF Dean, ... Science translational medicine 7 (311), 311ra173-311ra173, 2015 | 176 | 2015 |
| 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ... Chemical science 4 (8), 3110-3117, 2013 | 142 | 2013 |
| Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ... Journal of medicinal chemistry 57 (1), 42-55, 2014 | 119 | 2014 |
| Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ... Nature communications 11 (1), 1-13, 2020 | 117 | 2020 |
| Highly selective inhibition of histone demethylases by de novo macrocyclic peptides A Kawamura, M Münzel, T Kojima, C Yapp, B Bhushan, Y Goto, A Tumber, ... Nature communications 8 (1), 1-10, 2017 | 112 | 2017 |
| [1,2,4]Triazolo[4,3-a]phthalazines: Inhibitors of Diverse Bromodomains O Fedorov, H Lingard, C Wells, OP Monteiro, S Picaud, T Keates, C Yapp, ... Journal of medicinal chemistry 57 (2), 462-476, 2014 | 100 | 2014 |
| Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching M Philpott, CM Rogers, C Yapp, C Wells, JP Lambert, C Strain-Damerell, ... Epigenetics & chromatin 7 (1), 1-12, 2014 | 87 | 2014 |
| Potent and selective KDM5 inhibitor stops cellular demethylation of H3K4me3 at transcription start sites and proliferation of MM1S myeloma cells A Tumber, A Nuzzi, ES Hookway, SB Hatch, S Velupillai, C Johansson, ... Cell chemical biology 24 (3), 371-380, 2017 | 79 | 2017 |
| HSF1 phase transition mediates stress adaptation and cell fate decisions G Gaglia, R Rashid, C Yapp, GN Joshi, CG Li, SL Lindquist, KA Sarosiek, ... Nature cell biology 22 (2), 151-158, 2020 | 48 | 2020 |
| The response of tenocytes to commercial scaffolds used for rotator cuff repair. RD Smith, A Carr, SG Dakin, SJ Snelling, C Yapp, O Hakimi eCells and Materials Journal 30, 2016 | 45 | 2016 |
| The mechanical, structural, and compositional changes of tendon exposed to elastase TM Grant, C Yapp, Q Chen, JT Czernuszka, MS Thompson Annals of biomedical engineering 43 (10), 2477-2486, 2015 | 45 | 2015 |
| Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting … CL Sutherell, C Tallant, OP Monteiro, C Yapp, JE Fuchs, O Fedorov, ... Journal of medicinal chemistry 59 (10), 5095-5101, 2016 | 41 | 2016 |
| Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases CC Thinnes, A Tumber, C Yapp, G Scozzafava, T Yeh, MC Chan, TA Tran, ... Chemical Communications 51 (84), 15458-15461, 2015 | 40 | 2015 |
| Assessing histone demethylase inhibitors in cells: lessons learned SB Hatch, C Yapp, RC Montenegro, P Savitsky, V Gamble, A Tumber, ... Epigenetics & chromatin 10 (1), 1-17, 2017 | 38 | 2017 |
| Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer R Rashid, G Gaglia, YA Chen, JR Lin, Z Du, Z Maliga, D Schapiro, C Yapp, ... Scientific data 6 (1), 1-10, 2019 | 36 | 2019 |
