The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers CE Ashley, EC Carnes, GK Phillips, D Padilla, PN Durfee, PA Brown, ... Nature materials 10 (5), 389-397, 2011 | 1195 | 2011 |
Cell-specific delivery of diverse cargos by bacteriophage MS2 virus-like particles CE Ashley, EC Carnes, GK Phillips, PN Durfee, MD Buley, CA Lino, ... ACS nano 5 (7), 5729-5745, 2011 | 370 | 2011 |
Mesoporous silica nanoparticle-supported lipid bilayers (protocells) for active targeting and delivery to individual leukemia cells PN Durfee, YS Lin, DR Dunphy, AJ Muñiz, KS Butler, KR Humphrey, ... ACS nano 10 (9), 8325-8345, 2016 | 233 | 2016 |
Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics P Dogra, NL Adolphi, Z Wang, YS Lin, KS Butler, PN Durfee, JG Croissant, ... Nature Communications 9 (1), 4551, 2018 | 209 | 2018 |
Protocells: modular mesoporous silica nanoparticle‐supported lipid bilayers for drug delivery KS Butler, PN Durfee, C Theron, CE Ashley, EC Carnes, CJ Brinker small 12 (16), 2173-2185, 2016 | 201 | 2016 |
Versatile surface functionalization of metal–organic frameworks through direct metal coordination with a phenolic lipid enables diverse applications W Zhu, G Xiang, J Shang, J Guo, B Motevalli, P Durfee, JO Agola, ... Advanced Functional Materials 28 (16), 1705274, 2018 | 114 | 2018 |
Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples SI Brett, F Lucien, C Guo, KC Williams, Y Kim, PN Durfee, CJ Brinker, ... The Prostate 77 (13), 1335-1343, 2017 | 87 | 2017 |
Prostate extracellular vesicles in patient plasma as a liquid biopsy platform for prostate cancer using nanoscale flow cytometry CN Biggs, KM Siddiqui, AA Al-Zahrani, S Pardhan, SI Brett, QQ Guo, ... Oncotarget 7 (8), 8839, 2016 | 82 | 2016 |
Multifunctional protocells for enhanced penetration in 3D extracellular tumoral matrices MR Villegas, A Baeza, A Noureddine, PN Durfee, KS Butler, JO Agola, ... Chemistry of Materials 30 (1), 112-120, 2018 | 64 | 2018 |
Understanding the connection between nanoparticle uptake and cancer treatment efficacy using mathematical modeling TA Brocato, EN Coker, PN Durfee, YS Lin, J Townson, EF Wyckoff, ... Scientific reports 8 (1), 1-8, 2018 | 57 | 2018 |
Nanoscale flow cytometry to distinguish subpopulations of prostate extracellular vesicles in patient plasma RS Padda, FK Deng, SI Brett, CN Biggs, PN Durfee, CJ Brinker, ... The Prostate 79 (6), 592-603, 2019 | 49 | 2019 |
Induction of mucosal and systemic antibody responses against the HIV coreceptor CCR5 upon intramuscular immunization and aerosol delivery of a virus-like particle based vaccine Z Hunter, HD Smyth, P Durfee, B Chackerian Vaccine 28 (2), 403-414, 2009 | 48 | 2009 |
A novel approach for targeted delivery to motoneurons using cholera toxin-B modified protocells MAG Porras, PN Durfee, AM Gregory, GC Sieck, CJ Brinker, CB Mantilla Journal of neuroscience methods 273, 160-174, 2016 | 38 | 2016 |
Uptake and intracellular fate of cholera toxin subunit b-modified mesoporous silica nanoparticle-supported lipid bilayers (aka protocells) in motoneurons MAG Porras, P Durfee, S Giambini, GC Sieck, CJ Brinker, CB Mantilla Nanomedicine: Nanotechnology, Biology and Medicine 14 (3), 661-672, 2018 | 20 | 2018 |
Expression profiles of androgen independent bone metastatic prostate cancer cells indicate up-regulation of the putative serine-threonine kinase GS3955 M Bisoffi, I Klima, E Gresko, PN Durfee, WC Hines, JK Griffith, UE Studer, ... The Journal of urology 172 (3), 1145-1150, 2004 | 19 | 2004 |
Engineering of large-pore lipid-coated mesoporous silica nanoparticles for dual cargo delivery to cancer cells A Noureddine, EA Hjelvik, JG Croissant, PN Durfee, JO Agola, CJ Brinker Journal of Sol-Gel Science and Technology 89, 78-90, 2019 | 14 | 2019 |
Mesoporous silica nanoparticles and supported lipid bi-layer nanoparticles for biomedical applications CJ Brinker, PN Durfee, J Townson, YS Lin, SS Chou, J Erstling US Patent App. 15/757,269, 2018 | 13 | 2018 |
Core and Surface Modification of Mesoporous Silica Nanoparticles to Achieve Cell Specific Targeting In Vivo. CJ Brinker, J Townson, YS Lin, PN Durfee US Patent App. 15/023,093, 2016 | 12 | 2016 |
Osteotropic nanoparticles for prevention or treatment of bone metastases PN Durfee, CJ Brinker, YS Lin, H Leong US Patent 11,672,866, 2023 | 4 | 2023 |
Active targeting of cells by monosized protocells CJ Brinker, K Butler, PN Durfee US Patent 11,344,629, 2022 | 3 | 2022 |