| Structural insights into TDP-43 in nucleic-acid binding and domain interactions PH Kuo, LG Doudeva, YT Wang, CKJ Shen, HS Yuan Nucleic acids research 37 (6), 1799-1808, 2009 | 353 | 2009 |
| Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP H Liu, HW Peng, YS Cheng, HS Yuan, HF Yang-Yen Molecular and cellular biology, 2005 | 303 | 2005 |
| The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein TP Ko, CC Liao, WY Ku, KF Chak, HS Yuan Structure 7 (1), 91-102, 1999 | 228 | 1999 |
| Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients YS Fang, KJ Tsai, YJ Chang, P Kao, R Woods, PH Kuo, CC Wu, JY Liao, ... Nature communications 5 (1), 1-13, 2014 | 204 | 2014 |
| Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography GW Han, JY Lee, HK Song, C Chang, K Min, J Moon, DH Shin, ML Kopka, ... Journal of molecular biology 308 (2), 263-278, 2001 | 203 | 2001 |
| Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization Q Zhou, H Li, H Li, A Nakagawa, JLJ Lin, ES Lee, BL Harry, ... Science 353 (6297), 394-399, 2016 | 193 | 2016 |
| The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG-and TG-rich nucleic acids PH Kuo, CH Chiang, YT Wang, LG Doudeva, HS Yuan Nucleic acids research 42 (7), 4712-4722, 2014 | 190 | 2014 |
| The molecular structure of wild-type and a mutant Fis protein: relationship between mutational changes and recombinational enhancer function or DNA binding. HS Yuan, SE Finkel, JA Feng, M Kaczor-Grzeskowiak, RC Johnson, ... Proceedings of the National Academy of Sciences 88 (21), 9558-9562, 1991 | 184 | 1991 |
| DNA binding and cleavage by the periplasmic nuclease Vvn: a novel structure with a known active site CL Li, LI Hor, ZF Chang, LC Tsai, WZ Yang, HS Yuan The EMBO journal, 2003 | 132 | 2003 |
| Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing CL Li, WZ Yang, YP Chen, HS Yuan Nucleic acids research 36 (11), 3579-3589, 2008 | 124 | 2008 |
| The truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates YT Wang, PH Kuo, CH Chiang, JR Liang, YR Chen, S Wang, JCK Shen, ... Journal of Biological Chemistry 288 (13), 9049-9057, 2013 | 120 | 2013 |
| Crystal structure of Escherichia coli PNPase: central channel residues are involved in processive RNA degradation Z Shi, WZ Yang, S Lin-Chao, KF Chak, HS Yuan RNA 14 (11), 2361-2371, 2008 | 113 | 2008 |
| Structural studies of the pigeon cytosolic NADP+dependent malic enzyme Z Yang, H Zhang, HC Hung, CC Kuo, LC Tsai, HS Yuan, WY Chou, ... Protein science 11 (2), 332-341, 2002 | 95 | 2002 |
| Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors K Sargsyan, CC Lin, T Chen, C Grauffel, YP Chen, WZ Yang, HS Yuan, ... Chemical science 11 (36), 9904-9909, 2020 | 89 | 2020 |
| Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation CH Chiang, C Grauffel, LS Wu, PH Kuo, LG Doudeva, C Lim, CKJ Shen, ... Scientific reports 6 (1), 21581, 2016 | 86 | 2016 |
| Structural and functional insight into sugar-nonspecific nucleases in host defense KC Hsia, CL Li, HS Yuan Current opinion in structural biology 15 (1), 126-134, 2005 | 86 | 2005 |
| DNA binding and degradation by the HNH protein ColE7 KC Hsia, KF Chak, PH Liang, YS Cheng, WY Ku, HS Yuan Structure 12 (2), 205-214, 2004 | 85 | 2004 |
| The zinc ion in the HNH motif of the endonuclease domain of colicin E7 is not required for DNA binding but is essential for DNA hydrolysis WY Ku, YW Liu, YC Hsu, CC Liao, PH Liang, HS Yuan, KF Chak Nucleic acids research 30 (7), 1670-1678, 2002 | 80 | 2002 |
| The transactivation region of the Fis protein that controls sitespecific DNA inversion contains extended mobile βhairpin arms MK Safo, WZ Yang, L Corselli, SE Cramton, HS Yuan, RC Johnson The EMBO journal, 1997 | 79 | 1997 |
| Metal ions and phosphate binding in the HNH motif: crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ions MJ Sui, LC Tsai, KC Hsia, LG Doudeva, WY Ku, GW Han, HS Yuan Protein Science 11 (12), 2947-2957, 2002 | 75 | 2002 |
