| G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit distinct gating defects SG Bompadre, Y Sohma, M Li, TC Hwang The Journal of general physiology 129 (4), 285-298, 2007 | 183 | 2007 |
| Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR JH Guo, H Chen, YC Ruan, XL Zhang, XH Zhang, KL Fok, LL Tsang, ... Nature communications 5 (1), 4420, 2014 | 164 | 2014 |
| HCO3 − Transport in a Mathematical Model of the Pancreatic Ductal Epithelium Y Sohma, MA Gray, Y Imai, BE Argent The Journal of membrane biology 176, 77-100, 2000 | 91 | 2000 |
| Decrease in rat submandibular acinar cell volume during ACh stimulation T Nakahari, M Murakami, H Yoshida, M Miyamoto, Y Sohma, Y Imai American Journal of Physiology-Gastrointestinal and Liver Physiology 258 (6 …, 1990 | 86 | 1990 |
| On the mechanism of CFTR inhibition by a thiazolidinone derivative Z Kopeikin, Y Sohma, M Li, TC Hwang Journal of General Physiology 136 (6), 659-671, 2010 | 80 | 2010 |
| Potentiation of large conductance, Ca2+‐activated K+ (BK) channels by α5β1 integrin activation in arteriolar smooth muscle X Wu, Y Yang, P Gui, Y Sohma, GA Meininger, GE Davis, AP Braun, ... The Journal of physiology 586 (6), 1699-1713, 2008 | 70 | 2008 |
| CFTR gating I: Characterization of the ATP-dependent gating of a phosphorylation-independent CFTR channel (ΔR-CFTR) SG Bompadre, T Ai, JH Cho, X Wang, Y Sohma, M Li, TC Hwang The Journal of general physiology 125 (4), 361-375, 2005 | 68 | 2005 |
| Identifying the molecular target sites for CFTR potentiators GLPG1837 and VX-770 HI Yeh, L Qiu, Y Sohma, K Conrath, X Zou, TC Hwang Journal of General Physiology 151 (7), 912-928, 2019 | 64 | 2019 |
| A common mechanism for CFTR potentiators HI Yeh, Y Sohma, K Conrath, TC Hwang Journal of General Physiology 149 (12), 1105-1118, 2017 | 64 | 2017 |
| Curcumin and genistein additively potentiate G551D-CFTR YC Yu, H Miki, Y Nakamura, A Hanyuda, Y Matsuzaki, Y Abe, M Yasui, ... Journal of Cystic Fibrosis 10 (4), 243-252, 2011 | 58 | 2011 |
| CFTR gating II: Effects of nucleotide binding on the stability of open states SG Bompadre, JH Cho, X Wang, X Zou, Y Sohma, M Li, TC Hwang The Journal of general physiology 125 (4), 377-394, 2005 | 57 | 2005 |
| High affinity ATP/ADP analogues as new tools for studying CFTR gating Z Zhou, X Wang, M Li, Y Sohma, X Zou, TC Hwang The Journal of physiology 569 (2), 447-457, 2005 | 56 | 2005 |
| State-dependent modulation of CFTR gating by pyrophosphate MF Tsai, H Shimizu, Y Sohma, M Li, TC Hwang Journal of General Physiology 133 (4), 405-419, 2009 | 54 | 2009 |
| On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator YC Yu, Y Sohma, TC Hwang The Journal of physiology 594 (12), 3227-3244, 2016 | 49 | 2016 |
| Riluzole induces apoptotic cell death in human prostate cancer cells via endoplasmic reticulum stress K Akamatsu, MA Shibata, Y Ito, Y Sohma, H Azuma, Y Otsuki Anticancer research 29 (6), 2195-2204, 2009 | 49 | 2009 |
| Nonintegral stoichiometry in CFTR gating revealed by a pore-lining mutation KY Jih, Y Sohma, TC Hwang Journal of General Physiology 140 (4), 347-359, 2012 | 47 | 2012 |
| A novel SCN5A mutation V1340I in Brugada syndrome augmenting arrhythmias during febrile illness K Samani, G Wu, T Ai, M Shuraih, NS Mathuria, Z Li, Y Sohma, E Purevjav, ... Heart Rhythm 6 (9), 1318-1326, 2009 | 47 | 2009 |
| Mechanisms underlying regional differences in the Ca2+ sensitivity of BKCa current in arteriolar smooth muscle Y Yang, Y Sohma, Z Nourian, SR Ella, M Li, A Stupica, RJ Korthuis, ... The Journal of physiology 591 (5), 1277-1293, 2013 | 46 | 2013 |
| Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the … K Mio, T Ogura, M Mio, H Shimizu, TC Hwang, C Sato, Y Sohma Journal of Biological Chemistry 283 (44), 30300-30310, 2008 | 41 | 2008 |
| CFTR potentiators: from bench to bedside KY Jih, WY Lin, Y Sohma, TC Hwang Current opinion in pharmacology 34, 98-104, 2017 | 36 | 2017 |
