Alexander T Pearson
Alexander T Pearson
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Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer
JN Kather, AT Pearson, N Halama, D Jäger, J Krause, SH Loosen, A Marx, ...
Nature medicine 25 (7), 1054-1056, 2019
Mexiletine is an effective antimyotonia treatment in myotonic dystrophy type 1
EL Logigian, WB Martens, RT Moxley, MP McDermott, N Dilek, ...
Neurology 74 (18), 1441-1448, 2010
Postnatal exposure to methyl mercury from fish consumption: a review and new data from the Seychelles Child Development Study
GJ Myers, SW Thurston, AT Pearson, PW Davidson, C Cox, CF Shamlaye, ...
Neurotoxicology 30 (3), 338-349, 2009
Pan-cancer image-based detection of clinically actionable genetic alterations
JN Kather, LR Heij, HI Grabsch, C Loeffler, A Echle, HS Muti, J Krause, ...
Nature cancer 1 (8), 789-799, 2020
ALDH/CD44 identifies uniquely tumorigenic cancer stem cells in salivary gland mucoepidermoid carcinomas
A Adams, K Warner, AT Pearson, Z Zhang, HS Kim, D Mochizuki, ...
Oncotarget 6 (29), 26633, 2015
Patient-derived xenograft (PDX) tumors increase growth rate with time
AT Pearson, KA Finkel, KA Warner, F Nör, D Tice, MD Martins, TL Jackson, ...
Oncotarget 7 (7), 7993, 2016
The cancer microbiome: distinguishing direct and indirect effects requires a systemic view
JB Xavier, VB Young, J Skufca, F Ginty, T Testerman, AT Pearson, ...
Trends in cancer 6 (3), 192-204, 2020
Clinical-grade detection of microsatellite instability in colorectal tumors by deep learning
A Echle, HI Grabsch, P Quirke, PA van den Brandt, NP West, ...
Gastroenterology 159 (4), 1406-1416. e11, 2020
EGFL6 regulates the asymmetric division, maintenance, and metastasis of ALDH+ ovarian cancer cells
S Bai, P Ingram, YC Chen, N Deng, A Pearson, YS Niknafs, P O'Hayer, ...
Cancer research 76 (21), 6396-6409, 2016
Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
WY Wang, AT Pearson, ML Kutys, CK Choi, MA Wozniak, BM Baker, ...
APL bioengineering 2 (4), 046107, 2018
Anti-tumor effect of inhibition of IL-6 signaling in mucoepidermoid carcinoma
D Mochizuki, A Adams, KA Warner, Z Zhang, AT Pearson, K Misawa, ...
Oncotarget 6 (26), 22822, 2015
5T4-targeted therapy ablates cancer stem cells and prevents recurrence of head and neck squamous cell carcinoma
SA Kerk, KA Finkel, AT Pearson, KA Warner, Z Zhang, F Nör, VP Wagner, ...
Clinical Cancer Research 23 (10), 2516-2527, 2017
Ovarian Carcinoma‐Associated Mesenchymal Stem Cells Arise from Tissue‐Specific Normal Stroma
LG Coffman, AT Pearson, LG Frisbie, Z Freeman, E Christie, DD Bowtell, ...
Stem Cells 37 (2), 257-269, 2019
Deep learning in cancer pathology: a new generation of clinical biomarkers
A Echle, NT Rindtorff, TJ Brinker, T Luedde, AT Pearson, JN Kather
British journal of cancer 124 (4), 686-696, 2021
Machine learning can identify newly diagnosed patients with CLL at high risk of infection
R Agius, C Brieghel, MA Andersen, AT Pearson, B Ledergerber, ...
Nature communications 11 (1), 1-17, 2020
A phase II trial of the BCL-2 homolog domain 3 mimetic AT-101 in combination with docetaxel for recurrent, locally advanced, or metastatic head and neck cancer
PL Swiecicki, E Bellile, AG Sacco, AT Pearson, JMG Taylor, TL Jackson, ...
Investigational new drugs 34 (4), 481-489, 2016
Mucoepidermoid carcinoma: a comparison of histologic grading systems and relationship to MAML2 rearrangement and prognosis
NA Cipriani, JJ Lusardi, J McElherne, AT Pearson, AD Olivas, ...
The American journal of surgical pathology 43 (7), 885, 2019
A mathematical model for IL-6-mediated, stem cell driven tumor growth and targeted treatment
F Nazari, AT Pearson, JE Nör, TL Jackson
PLoS computational biology 14 (1), e1005920, 2018
A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target
ZT Freeman, TR Nirschl, DH Hovelson, RJ Johnston, JJ Engelhardt, ...
The Journal of clinical investigation 130 (3), 1405-1416, 2020
Association of immune-related adverse events (irAEs) with improved response, progression-free survival, and overall survival for patients with metastatic head and neck cancer …
CC Foster, S Kochanny, A Khattri, R Acharya, A Dekker, YHC Tan, ...
Journal of Clinical Oncology 36 (15_suppl), 6014-6014, 2018
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