Posttranscriptional control of T cell effector function by aerobic glycolysis CH Chang, JD Curtis, LB Maggi, B Faubert, AV Villarino, D O’Sullivan, ... Cell 153 (6), 1239-1251, 2013 | 2199 | 2013 |
Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization AK Jha, SCC Huang, A Sergushichev, V Lampropoulou, Y Ivanova, ... Immunity 42 (3), 419-430, 2015 | 1791 | 2015 |
Mitochondrial dynamics controls T cell fate through metabolic programming MD Buck, D O’Sullivan, RIK Geltink, JD Curtis, CH Chang, DE Sanin, ... Cell 166 (1), 63-76, 2016 | 1279 | 2016 |
Itaconate links inhibition of succinate dehydrogenase with macrophage metabolic remodeling and regulation of inflammation V Lampropoulou, A Sergushichev, M Bambouskova, S Nair, EE Vincent, ... Cell metabolism 24 (1), 158-166, 2016 | 1241 | 2016 |
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages SCC Huang, B Everts, Y Ivanova, D O'sullivan, M Nascimento, AM Smith, ... Nature immunology 15 (9), 846-855, 2014 | 1101 | 2014 |
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation B Everts, E Amiel, SCC Huang, AM Smith, CH Chang, WY Lam, ... Nature immunology 15 (4), 323-332, 2014 | 1097 | 2014 |
TREM2 maintains microglial metabolic fitness in Alzheimer’s disease TK Ulland, WM Song, SCC Huang, JD Ulrich, A Sergushichev, WL Beatty, ... Cell 170 (4), 649-663. e13, 2017 | 967 | 2017 |
Memory CD8+ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development D O’Sullivan, GJW van der Windt, SCC Huang, JD Curtis, CH Chang, ... Immunity 41 (1), 75-88, 2014 | 802 | 2014 |
Metabolic reprogramming mediated by the mTORC2-IRF4 signaling axis is essential for macrophage alternative activation SCC Huang, AM Smith, B Everts, M Colonna, EL Pearce, JD Schilling, ... Immunity 45 (4), 817-830, 2016 | 575 | 2016 |
CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability GJW Van Der Windt, D O’Sullivan, B Everts, SCC Huang, MD Buck, ... Proceedings of the National Academy of Sciences 110 (35), 14336-14341, 2013 | 551 | 2013 |
Navigating metabolic pathways to enhance antitumour immunity and immunotherapy X Li, M Wenes, P Romero, SCC Huang, SM Fendt, PC Ho Nature reviews Clinical oncology 16 (7), 425-441, 2019 | 531 | 2019 |
Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter TA Reese, BS Wakeman, HS Choi, MM Hufford, SC Huang, X Zhang, ... Science 345 (6196), 573-577, 2014 | 220 | 2014 |
Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival EL Gautier, S Ivanov, JW Williams, SCC Huang, G Marcelin, K Fairfax, ... Journal of Experimental Medicine 211 (8), 1525-1531, 2014 | 201 | 2014 |
Th2 responses in schistosomiasis K Fairfax, M Nascimento, SCC Huang, B Everts, EJ Pearce Seminars in immunopathology 34, 863-871, 2012 | 144 | 2012 |
Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12 B Everts, R Tussiwand, L Dreesen, KC Fairfax, SCC Huang, AM Smith, ... Journal of Experimental Medicine 213 (1), 35-51, 2016 | 129 | 2016 |
Ly6Chi Monocyte Recruitment Is Responsible for Th2 Associated Host-Protective Macrophage Accumulation in Liver Inflammation due to Schistosomiasis M Nascimento, SC Huang, A Smith, B Everts, W Lam, E Bassity, ... PLoS pathogens 10 (8), e1004282, 2014 | 103 | 2014 |
PERK is a critical metabolic hub for immunosuppressive function in macrophages LN Raines, H Zhao, Y Wang, HY Chen, H Gallart-Ayala, PC Hsueh, ... Nature immunology 23 (3), 431-445, 2022 | 100 | 2022 |
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity G Di Conza, CH Tsai, H Gallart-Ayala, YR Yu, F Franco, L Zaffalon, X Xie, ... Nature immunology 22 (11), 1403-1415, 2021 | 100 | 2021 |
Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways CM Taylor, Q Wang, BA Rosa, SCC Huang, K Powell, T Schedl, ... PLoS pathogens 9 (8), e1003505, 2013 | 100 | 2013 |
Mitochondrial membrane potential regulates nuclear gene expression in macrophages exposed to prostaglandin E2 DE Sanin, M Matsushita, RIK Geltink, KM Grzes, N van Teijlingen Bakker, ... Immunity 49 (6), 1021-1033. e6, 2018 | 99 | 2018 |