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Christian Schlein
Christian Schlein
MD, PhD, MBA. Principal investigator at University Medical Center Hamburg Eppendorf
在 uke.de 的電子郵件地址已通過驗證
標題
引用次數
引用次數
年份
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt, C Schlein, A Worthmann, ...
Nature communications 6 (1), 6356, 2015
5022015
The cold-induced lipokine 12, 13-diHOME promotes fatty acid transport into brown adipose tissue
MD Lynes, LO Leiria, M Lundh, A Bartelt, F Shamsi, TL Huang, ...
Nature medicine 23 (5), 631-637, 2017
4072017
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis
A Worthmann, C John, MC Rühlemann, M Baguhl, FA Heinsen, ...
Nature medicine 23 (7), 839-849, 2017
2822017
FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues
C Schlein, S Talukdar, M Heine, AW Fischer, LM Krott, SK Nilsson, ...
Cell metabolism 23 (3), 441-453, 2016
2732016
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ...
Nature medicine 24 (3), 292-303, 2018
1802018
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
Y Chen, JJ Buyel, MJW Hanssen, F Siegel, R Pan, J Naumann, M Schell, ...
Nature communications 7 (1), 11420, 2016
1732016
Lipolysis triggers a systemic insulin response essential for efficient energy replenishment of activated brown adipose tissue in mice
M Heine, AW Fischer, C Schlein, C Jung, LG Straub, K Gottschling, ...
Cell metabolism 28 (4), 644-655. e4, 2018
1572018
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
A Bartelt, C John, N Schaltenberg, JFP Berbée, A Worthmann, ...
Nature communications 8 (1), 15010, 2017
1542017
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine
B Niemann, S Haufs-Brusberg, L Puetz, M Feickert, MY Jaeckstein, ...
Nature 609 (7926), 361-368, 2022
972022
Intact innervation is essential for diet-induced recruitment of brown adipose tissue
AW Fischer, C Schlein, B Cannon, J Heeren, J Nedergaard
American Journal of Physiology-Endocrinology and Metabolism 316 (3), E487-E503, 2019
772019
Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation
AW Fischer, MY Jaeckstein, K Gottschling, M Heine, F Sass, N Mangels, ...
Cell metabolism 33 (3), 547-564. e7, 2021
542021
Endogenous fatty acid synthesis drives brown adipose tissue involution
C Schlein, AW Fischer, F Sass, A Worthmann, K Tödter, MY Jaeckstein, ...
Cell reports 34 (2), 2021
462021
Homozygosity for a partial deletion of apoprotein AV signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant
K Albers, C Schlein, K Wenner, P Lohse, A Bartelt, J Heeren, R Santer, ...
Atherosclerosis 233 (1), 97-103, 2014
372014
Course of HEV viremia and anti-HEV IgM/IgG response in asymptomatic blood donors
C Kraef, C Schlein, J Hiller, D Westhölter, U Denzer, T Horvatits, S Peine, ...
Journal of Clinical Virology 105, 26-30, 2018
292018
FoxO transcription factors are required for hepatic HDL cholesterol clearance
SX Lee, M Heine, C Schlein, R Ramakrishnan, J Liu, G Belnavis, I Haimi, ...
The Journal of clinical investigation 128 (4), 1615-1626, 2018
262018
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
F Sass, C Schlein, MY Jaeckstein, P Pertzborn, M Schweizer, T Schinke, ...
Molecular Metabolism 47, 101173, 2021
242021
Genetic dissection of tissue-specific apolipoprotein E function for hypercholesterolemia and diet-induced obesity
T Wagner, A Bartelt, C Schlein, J Heeren
PloS one 10 (12), e0145102, 2015
242015
PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles
AW Fischer, K Albers, C Schlein, F Sass, LM Krott, H Schmale, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (6 …, 2019
212019
Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice
AW Fischer, J Behrens, F Sass, C Schlein, M Heine, P Pertzborn, ...
Journal of Lipid Research 61 (11), 1377-1389, 2020
182020
Thermoneutrality-induced macrophage accumulation in brown adipose tissue does not impair the tissue’s competence for cold-induced thermogenic recruitment
AW Fischer, JMA De Jong, F Sass, C Schlein, J Heeren, N Petrovic
Frontiers in endocrinology 11, 568682, 2020
162020
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