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David W. Sanders
David W. Sanders
Assistant Professor, UT Southwestern
在 utsouthwestern.edu 的電子郵件地址已通過驗證 - 首頁
標題
引用次數
引用次數
年份
Distinct tau prion strains propagate in cells and mice and define different tauopathies
DW Sanders, SK Kaufman, SL DeVos, AM Sharma, H Mirbaha, A Li, ...
Neuron 82 (6), 1271-1288, 2014
10162014
Neuronal activity enhances tau propagation and tau pathology in vivo
JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, ...
Nature neuroscience 19 (8), 1085-1092, 2016
6912016
Liquid nuclear condensates mechanically sense and restructure the genome
Y Shin, YC Chang, DSW Lee, J Berry, DW Sanders, P Ronceray, ...
Cell 175 (6), 1481-1491. e13, 2018
5762018
Competing protein-RNA interaction networks control multiphase intracellular organization
DW Sanders, N Kedersha, DSW Lee, AR Strom, V Drake, JA Riback, ...
Cell 181 (2), 306-324. e28, 2020
5702020
Composition-dependent thermodynamics of intracellular phase separation
JA Riback, L Zhu, MC Ferrolino, M Tolbert, DM Mitrea, DW Sanders, ...
Nature 581 (7807), 209-214, 2020
4782020
Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo
SK Kaufman, DW Sanders, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, ...
Neuron 92 (4), 796-812, 2016
4112016
Propagation of prions causing synucleinopathies in cultured cells
AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ...
Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015
2442015
Tau trimers are the minimal propagation unit spontaneously internalized to seed intracellular aggregation
H Mirbaha, BB Holmes, DW Sanders, J Bieschke, MI Diamond
Journal of Biological Chemistry 290 (24), 14893-14903, 2015
2392015
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation
DW Sanders, CC Jumper, PJ Ackerman, D Bracha, A Donlic, H Kim, ...
Elife 10, e65962, 2021
1852021
Nucleation landscape of biomolecular condensates
SF Shimobayashi, P Ronceray, DW Sanders, MP Haataja, ...
Nature 599 (7885), 503-506, 2021
1302021
Prions and protein assemblies that convey biological information in health and disease (REVIEW)
DW Sanders, SK Kaufman, BB Holmes, MI Diamond
Neuron 89 (3), 433-448, 2016
892016
Size distributions of intracellular condensates reflect competition between coalescence and nucleation
DSW Lee, CH Choi, DW Sanders, L Beckers, JA Riback, CP Brangwynne, ...
Nature Physics 19 (4), 586-596, 2023
292023
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
I Saha, P Yuste-Checa, M Da Silva Padilha, Q Guo, R Körner, ...
Nature Communications 14 (1), 560, 2023
29*2023
The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition
G Eskandari-Sedighi, N Daude, H Gapeshina, DW Sanders, ...
Molecular neurodegeneration 12 (1), 72, 2017
192017
Neurodegenerative disease: RNA repeats put a freeze on cells (COMMENTARY)
DW Sanders, CP Brangwynne
Nature 546 (7657), 215-216, 2017
102017
Poly (GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions
J Park, Y Wu, W Shao, TF Gendron, SJF van der Spek, G Sultanakhmetov, ...
Cell Reports 42 (8), 2023
52023
DnaJC7 specifically regulates tau seeding
VA Perez, DW Sanders, A Mendoza-Oliva, BE Stopschinski, V Mullapudi, ...
Elife 12, e86936, 2023
52023
Condensate interfaces can accelerate protein aggregation
CH Choi, DSW Lee, DW Sanders, CP Brangwynne
Biophysical Journal, 2023
42023
Spatially constrained transcriptional sources drive asphericity of intracellular liquids
JA Riback, DSW Lee, JM Eeftens, DW Sanders, L Beckers, ...
Biophysical Journal 120 (3), 278a, 2021
22021
Synthetic peptides for dissolving tau inclusions
CP Brangwynne, DW Sanders
US Patent App. 18/124,252, 2023
2023
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