TRIM21 ubiquitylates SQSTM1/p62 and suppresses protein sequestration to regulate redox homeostasis JA Pan, Y Sun, YP Jiang, AJ Bott, N Jaber, Z Dou, B Yang, JS Chen, ... Molecular cell 61 (5), 720-733, 2016 | 242 | 2016 |
Oncogenic Myc induces expression of glutamine synthetase through promoter demethylation AJ Bott, IC Peng, Y Fan, B Faubert, L Zhao, J Li, S Neidler, Y Sun, N Jaber, ... Cell metabolism 22 (6), 1068-1077, 2015 | 242 | 2015 |
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure AA Cluntun, R Badolia, S Lettlova, KM Parnell, TS Shankar, NA Diakos, ... Cell metabolism 33 (3), 629-648. e10, 2021 | 169 | 2021 |
Glutamine anabolism plays a critical role in pancreatic cancer by coupling carbon and nitrogen metabolism AJ Bott, J Shen, C Tonelli, L Zhan, N Sivaram, YP Jiang, X Yu, V Bhatt, ... Cell reports 29 (5), 1287-1298. e6, 2019 | 141 | 2019 |
Regulation of tumor initiation by the mitochondrial pyruvate carrier CL Bensard, DR Wisidagama, KA Olson, JA Berg, NM Krah, JC Schell, ... Cell metabolism 31 (2), 284-300. e7, 2020 | 136 | 2020 |
The pleiotropic effects of glutamine metabolism in cancer AJ Bott, S Maimouni, WX Zong Cancers 11 (6), 770, 2019 | 110 | 2019 |
SCCA1/SERPINB3 promotes oncogenesis and epithelial–mesenchymal transition via the unfolded protein response and IL6 signaling N Sheshadri, JM Catanzaro, AJ Bott, Y Sun, E Ullman, EI Chen, JA Pan, ... Cancer research 74 (21), 6318-6329, 2014 | 82 | 2014 |
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase KG Hicks, AA Cluntun, HL Schubert, SR Hackett, JA Berg, PG Leonard, ... Science 379 (6636), 996-1003, 2023 | 56 | 2023 |
Glutamine synthetase limits β-catenin–mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1 W Dai, J Shen, J Yan, AJ Bott, S Maimouni, HQ Daguplo, Y Wang, ... The Journal of clinical investigation 132 (24), 2022 | 25 | 2022 |
XPRESSyourself: Enhancing, standardizing, and automating ribosome profiling computational analyses yields improved insight into data JA Berg, JR Belyeu, JT Morgan, Y Ouyang, AJ Bott, AR Quinlan, J Gertz, ... PLOS Computational Biology 16 (1), e1007625, 2020 | 18 | 2020 |
SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC CF Ruiz, ED Montal, JA Haley, AJ Bott, JD Haley FASEB journal: official publication of the Federation of American Societies …, 2020 | 14 | 2020 |
Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway P Wei, AJ Bott, AA Cluntun, JT Morgan, CN Cunningham, JC Schell, ... Science Advances 8 (39), eabq0117, 2022 | 13 | 2022 |
Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction JM Winter, HL Fresenius, CN Cunningham, P Wei, HR Keys, J Berg, ... Elife 11, e82860, 2022 | 10 | 2022 |
Maestro of the SereNADe: SLC25A51 orchestrates mitochondrial NAD+ Y Ouyang, AJ Bott, J Rutter Trends in biochemical sciences 46 (5), 348-350, 2021 | 8 | 2021 |
Spectrophotometric determination of glutamine synthetase activity in cultured cells IC Peng, AJ Bott, WX Zong Bio-protocol 6 (19), e1959-e1959, 2016 | 5 | 2016 |
XPRESSyourself: enhancing and automating the ribosome profiling and RNA-Seq analysis toolkit JA Berg, JR Belyeu, JT Morgan, AJ Bott, Y Ouyang, AR Quinlan, J Gertz, ... bioRxiv, 704320, 2019 | 2 | 2019 |
Abstract 2440 Regulation of the Mitochondrial Pyruvate Carrier by the Wnt/beta-catenin pathway L Cedeņo-Rosario, N Abdi, A Bott, J Youngs, J Rutter Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Abstract C058: Identifying cell-intrinsic drivers of transcriptional plasticity in pancreatic cancer YE Tong, WE Katan, A Bott, J Joung, AK Shalek, PS Winter, S Raghavan Cancer Research 84 (2_Supplement), C058-C058, 2024 | | 2024 |
SLC7A5 is required for citrulline-dependent growth in arginine limited conditions KN Dunlap, A Bender, A Bowles, AJ Bott, J Rutter, G Ducker bioRxiv, 2024.06. 27.600869, 2024 | | 2024 |
Mitochondrial pyruvate supports lymphoma proliferation by fueling a non-canonical glutamine metabolism pathway P Wei, AJ Bott, AA Cluntun, JT Morgan, CN Cunningham, JC Schell, ... bioRxiv, 2021.08. 26.457847, 2021 | | 2021 |