Copper induces cell death by targeting lipoylated TCA cycle proteins P Tsvetkov, S Coy, B Petrova, M Dreishpoon, A Verma, M Abdusamad, ... Science 375 (6586), 1254-1261, 2022 | 1905 | 2022 |
Physiologic medium rewires cellular metabolism and reveals uric acid as an endogenous inhibitor of UMP synthase JR Cantor, M Abu-Remaileh, N Kanarek, E Freinkman, X Gao, ... Cell 169 (2), 258-272. e17, 2017 | 478 | 2017 |
Regulation of NF‐κB by ubiquitination and degradation of the IκBs N Kanarek, Y Ben‐Neriah Immunological reviews 246 (1), 77-94, 2012 | 363 | 2012 |
Histidine catabolism is a major determinant of methotrexate sensitivity N Kanarek, HR Keys, JR Cantor, CA Lewis, SH Chan, T Kunchok, ... Nature 559 (7715), 632-636, 2018 | 275 | 2018 |
Dietary modifications for enhanced cancer therapy N Kanarek, B Petrova, DM Sabatini Nature 579 (7800), 507-517, 2020 | 263 | 2020 |
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition YD Shaul, E Freinkman, WC Comb, JR Cantor, WL Tam, P Thiru, D Kim, ... Cell 158 (5), 1094-1109, 2014 | 222 | 2014 |
mTOR generates an auto-amplification loop by triggering the βTrCP-and CK1α-dependent degradation of DEPTOR S Duan, JR Skaar, S Kuchay, A Toschi, N Kanarek, Y Ben-Neriah, ... Molecular cell 44 (2), 317-324, 2011 | 212 | 2011 |
Human and Mouse VEGFA-Amplified Hepatocellular Carcinomas Are Highly Sensitive to Sorafenib Treatment E Horwitz, I Stein, M Andreozzi, J Nemeth, A Shoham, O Pappo, ... Cancer discovery 4 (6), 730-743, 2014 | 191 | 2014 |
Ubiquitination and degradation of the inhibitors of NF-κB N Kanarek, N London, O Schueler-Furman, Y Ben-Neriah Cold Spring Harbor perspectives in biology 2 (2), a000166, 2010 | 164 | 2010 |
Critical role for IL-1β in DNA damage-induced mucositis N Kanarek, SI Grivennikov, M Leshets, A Lasry, I Alkalay, E Horwitz, ... Proceedings of the National Academy of Sciences 111 (6), E702-E711, 2014 | 58 | 2014 |
Cell-based genomic recorded accumulative memory JM Jacobson, N Jakimo, N Kanarek, D Sabatini US Patent 11,326,209, 2022 | 44 | 2022 |
Integrative metabolomics to identify molecular signatures of responses to vaccines and infections J Diray-Arce, MG Conti, B Petrova, N Kanarek, A Angelidou, O Levy Metabolites 10 (12), 492, 2020 | 44 | 2020 |
Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCFβ-TrCP by single substrate depletion N Kanarek, E Horwitz, I Mayan, M Leshets, G Cojocaru, M Davis, ... Genes & development 24 (5), 470-477, 2010 | 44 | 2010 |
Segregation between acquisition and long‐term memory in sensorimotor learning N Zach, N Kanarek, D Inbar, Y Grinvald, T Milestein, E Vaadia European journal of neuroscience 22 (9), 2357-2362, 2005 | 26 | 2005 |
NADH ties one-carbon metabolism to cellular respiration AG Maynard, N Kanarek Cell metabolism 31 (4), 660-662, 2020 | 25 | 2020 |
Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment. Cancer Discov. 2014; 4: 730–743. doi: 10.1158/2159-8290 E Horwitz, I Stein, M Andreozzi, J Nemeth, A Shoham, O Pappo, ... CD-13-0782.[Abstract][CrossRef][Google Scholar], 0 | 24 | |
FDX1 regulates cellular protein lipoylation through direct binding to LIAS MB Dreishpoon, NR Bick, B Petrova, DM Warui, A Cameron, SJ Booker, ... Journal of Biological Chemistry 299 (9), 2023 | 23 | 2023 |
The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase LN Heppler, S Attarha, R Persaud, JI Brown, P Wang, B Petrova, I Tošić, ... Journal of Biological Chemistry 298 (2), 2022 | 19 | 2022 |
Choroid plexus-CSF-targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy A Jang, B Petrova, TC Cheong, ME Zawadzki, JK Jones, AJ Culhane, ... Neuron 110 (20), 3288-3301. e8, 2022 | 14 | 2022 |
Redox metabolism measurement in mammalian cells and tissues by LC-MS B Petrova, A Warren, NY Vital, AJ Culhane, AG Maynard, A Wong, ... Metabolites 11 (5), 313, 2021 | 14 | 2021 |