Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease JH Kim, JM Auerbach, JA Rodríguez-Gómez, I Velasco, D Gavin, ... Nature 418 (6893), 50-56, 2002 | 2076 | 2002 |
Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach KS Bankiewicz, JL Eberling, M Kohutnicka, W Jagust, P Pivirotto, ... Experimental neurology 164 (1), 2-14, 2000 | 423 | 2000 |
Safety and tolerability of putaminal AADC gene therapy for Parkinson disease CW Christine, PA Starr, PS Larson, JL Eberling, WJ Jagust, RA Hawkins, ... Neurology 73 (20), 1662-1669, 2009 | 379 | 2009 |
Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion DM Lieberman, DW Laske, PF Morrison, KS Bankiewicz, EH Oldfield Journal of neurosurgery 82 (6), 1021-1029, 1995 | 378 | 1995 |
Results from a phase I safety trial of hAADC gene therapy for Parkinson disease JL Eberling, WJ Jagust, CW Christine, P Starr, P Larson, KS Bankiewicz, ... Neurology 70 (21), 1980-1983, 2008 | 354 | 2008 |
Hemiparkinsonism in monkeys after unilateral internal carotid artery artery infusion of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) KS Bankiewicz, EH Oldfield, CC Chiueh, JL Doppman, DM Jacobowitz, ... Life sciences 39 (1), 7-16, 1986 | 348 | 1986 |
Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging R Saito, JR Bringas, TR McKnight, MF Wendland, C Mamot, ... Cancer research 64 (7), 2572-2579, 2004 | 306 | 2004 |
Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC KS Bankiewicz, J Forsayeth, JL Eberling, R Sanchez-Pernaute, P Pivirotto, ... Molecular Therapy 14 (4), 564-570, 2006 | 285 | 2006 |
A 6-hydroxydopamine-induced selective parkinsonian rat model DA Perese, J Ulman, J Viola, SE Ewing, KS Bankiewicz Brain research 494 (2), 285-293, 1989 | 280 | 1989 |
The “perivascular pump” driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain P Hadaczek, Y Yamashita, H Mirek, L Tamas, MC Bohn, C Noble, ... Molecular Therapy 14 (1), 69-78, 2006 | 241 | 2006 |
Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates L Samaranch, EA Salegio, W San Sebastian, AP Kells, KD Foust, ... Human gene therapy 23 (4), 382-389, 2012 | 234 | 2012 |
Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease G Mittermeyer, CW Christine, KH Rosenbluth, SL Baker, P Starr, P Larson, ... Human gene therapy 23 (4), 377-381, 2012 | 231 | 2012 |
Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents MT Krauze, R Saito, C Noble, M Tamas, J Bringas, JW Park, MS Berger, ... Journal of neurosurgery 103 (5), 923-929, 2005 | 214 | 2005 |
Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study M Herkenham, MD Little, K Bankiewicz, SC Yang, SP Markey, ... Neuroscience 40 (1), 133-158, 1991 | 196 | 1991 |
Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy CO Noble, MT Krauze, DC Drummond, Y Yamashita, R Saito, MS Berger, ... Cancer research 66 (5), 2801-2806, 2006 | 182 | 2006 |
In vitro generation and transplantation of precursor‐derived human dopamine neurons R Sánchez‐Pernaute, L Studer, KS Bankiewicz, EO Major, RDG McKay Journal of neuroscience research 65 (4), 284-288, 2001 | 176 | 2001 |
Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and … JF Hamilton, PF Morrison, MY Chen, J Harvey-White, RS Pernaute, ... Experimental neurology 168 (1), 155-161, 2001 | 174 | 2001 |
Transient behavioral recovery in hemiparkinsonian primates after adrenal medullary allografts KS Bankiewicz, RJ Plunkett, IJ Kopin, DM Jacobowitz, WT London, ... Progress in brain research 78, 543-549, 1988 | 167 | 1988 |
A 6-hydroxydopamine-induced selective parkinsonian rat model: further biochemical and behavioral characterization J Thomas, J Wang, H Takubo, J Sheng, S de Jesus, KS Bankiewicz Experimental neurology 126 (2), 159-167, 1994 | 166 | 1994 |
Extensive distribution of liposomes in rodent brains and brain tumors following convection-enhanced delivery C Mamot, JB Nguyen, M Pourdehnad, P Hadaczek, R Saito, JR Bringas, ... Journal of neuro-oncology 68 (1), 1-9, 2004 | 164 | 2004 |