|Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease|
JH Kim, JM Auerbach, JA Rodríguez-Gómez, I Velasco, D Gavin, ...
Nature 418 (6893), 50-56, 2002
|Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach|
KS Bankiewicz, JL Eberling, M Kohutnicka, W Jagust, P Pivirotto, ...
Experimental neurology 164 (1), 2-14, 2000
|Safety and tolerability of putaminal AADC gene therapy for Parkinson disease|
CW Christine, PA Starr, PS Larson, JL Eberling, WJ Jagust, RA Hawkins, ...
Neurology 73 (20), 1662-1669, 2009
|Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion|
DM Lieberman, DW Laske, PF Morrison, KS Bankiewicz, EH Oldfield
Journal of neurosurgery 82 (6), 1021-1029, 1995
|Results from a phase I safety trial of hAADC gene therapy for Parkinson disease|
JL Eberling, WJ Jagust, CW Christine, P Starr, P Larson, KS Bankiewicz, ...
Neurology 70 (21), 1980-1983, 2008
|Hemiparkinsonism in monkeys after unilateral internal carotid artery artery infusion of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)|
KS Bankiewicz, EH Oldfield, CC Chiueh, JL Doppman, DM Jacobowitz, ...
Life sciences 39 (1), 7-16, 1986
|Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging|
R Saito, JR Bringas, TR McKnight, MF Wendland, C Mamot, ...
Cancer research 64 (7), 2572-2579, 2004
|Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC|
KS Bankiewicz, J Forsayeth, JL Eberling, R Sanchez-Pernaute, P Pivirotto, ...
Molecular Therapy 14 (4), 564-570, 2006
|A 6-hydroxydopamine-induced selective parkinsonian rat model|
DA Perese, J Ulman, J Viola, SE Ewing, KS Bankiewicz
Brain research 494 (2), 285-293, 1989
|The “perivascular pump” driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain|
P Hadaczek, Y Yamashita, H Mirek, L Tamas, MC Bohn, C Noble, ...
Molecular Therapy 14 (1), 69-78, 2006
|Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates|
L Samaranch, EA Salegio, W San Sebastian, AP Kells, KD Foust, ...
Human gene therapy 23 (4), 382-389, 2012
|Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease|
G Mittermeyer, CW Christine, KH Rosenbluth, SL Baker, P Starr, P Larson, ...
Human gene therapy 23 (4), 377-381, 2012
|Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents|
MT Krauze, R Saito, C Noble, M Tamas, J Bringas, JW Park, MS Berger, ...
Journal of neurosurgery 103 (5), 923-929, 2005
|Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study|
M Herkenham, MD Little, K Bankiewicz, SC Yang, SP Markey, ...
Neuroscience 40 (1), 133-158, 1991
|Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy|
CO Noble, MT Krauze, DC Drummond, Y Yamashita, R Saito, MS Berger, ...
Cancer research 66 (5), 2801-2806, 2006
|In vitro generation and transplantation of precursor‐derived human dopamine neurons|
R Sánchez‐Pernaute, L Studer, KS Bankiewicz, EO Major, RDG McKay
Journal of neuroscience research 65 (4), 284-288, 2001
|Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and …|
JF Hamilton, PF Morrison, MY Chen, J Harvey-White, RS Pernaute, ...
Experimental neurology 168 (1), 155-161, 2001
|Transient behavioral recovery in hemiparkinsonian primates after adrenal medullary allografts|
KS Bankiewicz, RJ Plunkett, IJ Kopin, DM Jacobowitz, WT London, ...
Progress in brain research 78, 543-549, 1988
|A 6-hydroxydopamine-induced selective parkinsonian rat model: further biochemical and behavioral characterization|
J Thomas, J Wang, H Takubo, J Sheng, S de Jesus, KS Bankiewicz
Experimental neurology 126 (2), 159-167, 1994
|Extensive distribution of liposomes in rodent brains and brain tumors following convection-enhanced delivery|
C Mamot, JB Nguyen, M Pourdehnad, P Hadaczek, R Saito, JR Bringas, ...
Journal of neuro-oncology 68 (1), 1-9, 2004