TLR3 deficiency in patients with herpes simplex encephalitis SY Zhang, E Jouanguy, S Ugolini, A Smahi, G Elain, P Romero, D Segal, ... science 317 (5844), 1522-1527, 2007 | 1290 | 2007 |
Pyogenic bacterial infections in humans with IRAK-4 deficiency C Picard, A Puel, M Bonnet, CL Ku, J Bustamante, K Yang, C Soudais, ... Science 299 (5615), 2076-2079, 2003 | 1089 | 2003 |
Pyogenic bacterial infections in humans with MyD88 deficiency H Von Bernuth, C Picard, Z Jin, R Pankla, H Xiao, CL Ku, M Chrabieh, ... Science 321 (5889), 691-696, 2008 | 883 | 2008 |
Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency C Picard, H Von Bernuth, P Ghandil, M Chrabieh, O Levy, PD Arkwright, ... Medicine 89 (6), 403-425, 2010 | 486 | 2010 |
Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity CL Ku, H Von Bernuth, C Picard, SY Zhang, HH Chang, K Yang, ... The Journal of experimental medicine 204 (10), 2407-2422, 2007 | 479 | 2007 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 440 | 2021 |
Human TLR-7-,-8-, and-9-mediated induction of IFN-α/β and-λ is IRAK-4 dependent and redundant for protective immunity to viruses K Yang, A Puel, S Zhang, C Eidenschenk, CL Ku, A Casrouge, C Picard, ... Immunity 23 (5), 465-478, 2005 | 350 | 2005 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 334 | 2021 |
X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production O Filipe-Santos, J Bustamante, MH Haverkamp, E Vinolo, CL Ku, A Puel, ... The Journal of experimental medicine 203 (7), 1745-1759, 2006 | 316 | 2006 |
Inherited disorders of NF-κB-mediated immunity in man A Puel, C Picard, CL Ku, A Smahi, JL Casanova Current opinion in immunology 16 (1), 34-41, 2004 | 221 | 2004 |
Primary immunodeficiencies associated with pneumococcal disease C Picard, A Puel, J Bustamante, CL Ku, JL Casanova Current opinion in allergy and clinical immunology 3 (6), 451-459, 2003 | 213 | 2003 |
Bacillus Calmette Guérin triggers the IL‐12/IFN‐γ axis by an IRAK‐4‐and NEMO‐dependent, non‐cognate interaction between monocytes, NK, and T lymphocytes J Feinberg, C Fieschi, R Doffinger, M Feinberg, T Leclerc, ... European journal of immunology 34 (11), 3276-3284, 2004 | 181 | 2004 |
Anti–IFN-γ autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB1* 16: 02 and HLA-DQB1* 05: 02 and the reactivation of … CY Chi, CC Chu, JP Liu, CH Lin, MW Ho, WJ Lo, PC Lin, HJ Chen, ... Blood, The Journal of the American Society of Hematology 121 (8), 1357-1366, 2013 | 171 | 2013 |
IRAK4 and NEMO mutations in otherwise healthy children with recurrent invasive pneumococcal disease CL Ku, C Picard, M Erdös, A Jeurissen, J Bustamante, A Puel, ... Journal of medical genetics 44 (1), 16-23, 2007 | 168 | 2007 |
Inherited disorders of human Toll‐like receptor signaling: immunological implications CL Ku, K Yang, J Bustamante, A Puel, H Von Bernuth, OF Santos, ... Immunological reviews 203 (1), 10-20, 2005 | 162 | 2005 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 128 | 2022 |
Inherited human IFN-γ deficiency underlies mycobacterial disease G Kerner, J Rosain, A Guérin, A Al-Khabaz, C Oleaga-Quintas, ... The Journal of clinical investigation 130 (6), 3158-3171, 2020 | 108 | 2020 |
Clinical manifestations, course, and outcome of patients with neutralizing anti-interferon-γ autoantibodies and disseminated nontuberculous mycobacterial infections CY Chi, CH Lin, MW Ho, JY Ding, WC Huang, HP Shih, CF Yeh, CP Fung, ... Medicine 95 (25), e3927, 2016 | 108 | 2016 |
The NEMO mutation creating the most-upstream premature stop codon is hypomorphic because of a reinitiation of translation A Puel, J Reichenbach, J Bustamante, CL Ku, J Feinberg, R Döffinger, ... The American Journal of Human Genetics 78 (4), 691-701, 2006 | 107 | 2006 |
Identification of a major epitope by anti-interferon-γ autoantibodies in patients with mycobacterial disease CH Lin, CY Chi, HP Shih, JY Ding, CC Lo, SY Wang, CY Kuo, CF Yeh, ... Nature medicine 22 (9), 994-1001, 2016 | 91 | 2016 |