Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression GM Lord, G Matarese, JK Howard, RJ Baker, SR Bloom, RI Lechler Nature 394 (6696), 897-901, 1998 | 2940 | 1998 |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ... Nature 478 (7367), 103-109, 2011 | 2294 | 2011 |
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency IS Farooqi, G Matarese, GM Lord, JM Keogh, E Lawrence, C Agwu, ... The Journal of clinical investigation 110 (8), 1093-1103, 2002 | 2030 | 2002 |
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease B Afzali, G Lombardi, RI Lechler, GM Lord Clinical & Experimental Immunology 148 (1), 32-46, 2007 | 1136 | 2007 |
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system WS Garrett, GM Lord, S Punit, G Lugo-Villarino, SK Mazmanian, S Ito, ... Cell 131 (1), 33-45, 2007 | 1118 | 2007 |
Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice JK Howard, GM Lord, G Matarese, S Vendetti, MA Ghatei, MA Ritter, ... The Journal of clinical investigation 104 (8), 1051-1059, 1999 | 724 | 1999 |
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans P Sagoo, E Perucha, B Sawitzki, S Tomiuk, DA Stephens, P Miqueu, ... The Journal of clinical investigation 120 (6), 1848-1861, 2010 | 594 | 2010 |
T-bet: a bridge between innate and adaptive immunity V Lazarevic, LH Glimcher, GM Lord Nature Reviews Immunology 13 (11), 777-789, 2013 | 561 | 2013 |
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure LV Wain, GC Verwoert, PF O'reilly, G Shi, T Johnson, AD Johnson, ... Nature genetics 43 (10), 1005-1011, 2011 | 504 | 2011 |
Requirement for leptin in the induction and progression of autoimmune encephalomyelitis G Matarese, A Di Giacomo, V Sanna, GM Lord, JK Howard, A Di Tuoro, ... The Journal of Immunology 166 (10), 5909-5916, 2001 | 434 | 2001 |
Nephropathy caused by Chinese herbs in the UK GM Lord, R Tagore, T Cook, P Gower, CD Pusey The Lancet 354 (9177), 481-482, 1999 | 419 | 1999 |
T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements A Kanhere, A Hertweck, U Bhatia, MR Gökmen, E Perucha, I Jackson, ... Nature communications 3 (1), 1268, 2012 | 383 | 2012 |
Recent developments in the transcriptional regulation of cytolytic effector cells LH Glimcher, MJ Townsend, BM Sullivan, GM Lord Nature Reviews Immunology 4 (11), 900-911, 2004 | 381 | 2004 |
The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells N Powell, AW Walker, E Stolarczyk, JB Canavan, MR Gökmen, E Marks, ... Immunity 37 (4), 674-684, 2012 | 364 | 2012 |
A genome-wide association study of anorexia nervosa V Boraska, CS Franklin, JAB Floyd, LM Thornton, LM Huckins, L Southam, ... Molecular psychiatry 19 (10), 1085-1094, 2014 | 344 | 2014 |
Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes HG Evans, T Suddason, I Jackson, LS Taams, GM Lord Proceedings of the National Academy of Sciences 104 (43), 17034-17039, 2007 | 338 | 2007 |
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking GM Lord, RM Rao, H Choe, BM Sullivan, AH Lichtman, FW Luscinskas, ... Blood 106 (10), 3432-3439, 2005 | 330 | 2005 |
Genetic loci influencing kidney function and chronic kidney disease JC Chambers, W Zhang, GM Lord, P Van Der Harst, DA Lawlor, JS Sehmi, ... Nature genetics 42 (5), 373-375, 2010 | 325 | 2010 |
Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells J Cardone, G Le Friec, P Vantourout, A Roberts, A Fuchs, I Jackson, ... Nature immunology 11 (9), 862-871, 2010 | 307 | 2010 |
Balancing susceptibility to infection and autoimmunity: a role for leptin? G Matarese, A La Cava, V Sanna, GM Lord, RI Lechler, S Fontana, ... Trends in immunology 23 (4), 182-187, 2002 | 295 | 2002 |