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| The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4γ and the translational repressors 4E-binding proteins S Mader, H Lee, A Pause, N Sonenberg Molecular and cellular biology, 1995 | 923 | 1995 |
| mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ... Cell metabolism 18 (5), 698-711, 2013 | 836 | 2013 |
| PHAS-I as a link between mitogen-activated protein kinase and translation initiation TA Lin, X Kong, TAJ Haystead, A Pause, G Belsham, N Sonenberg, ... Science 266 (5185), 653-656, 1994 | 827 | 1994 |
| Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF‐4A. A Pause, N Sonenberg The EMBO journal 11 (7), 2643-2654, 1992 | 808 | 1992 |
| Repression of cap‐dependent translation by 4E‐binding protein 1: competition with p220 for binding to eukaryotic initiation factor‐4E. A Haghighat, S Mader, A Pause, N Sonenberg The EMBO journal 14 (22), 5701-5709, 1995 | 790 | 1995 |
| Inhibition of transcription elongation by the VHL tumor suppressor protein DR Duan, A Pause, WH Burgess, T Aso, DYT Chen, KP Garrett, ... Science 269 (5229), 1402-1406, 1995 | 743 | 1995 |
| The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins A Pause, S Lee, RA Worrell, DYT Chen, WH Burgess, WM Linehan, ... Proceedings of the National Academy of Sciences 94 (6), 2156-2161, 1997 | 648 | 1997 |
| Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex K Iwai, K Yamanaka, T Kamura, N Minato, RC Conaway, JW Conaway, ... Proceedings of the National Academy of Sciences 96 (22), 12436-12441, 1999 | 630 | 1999 |
| The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5'secondary structure. YV Svitkin, A Pause, A Haghighat, S Pyronnet, G Witherell, GJ Belsham, ... Rna 7 (3), 382-394, 2001 | 606 | 2001 |
| AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species RC Rabinovitch, B Samborska, B Faubert, EH Ma, SP Gravel, ... Cell reports 21 (1), 1-9, 2017 | 496 | 2017 |
| Dominant negative mutants of mammalian translation initiation factor eIF‐4A define a critical role for eIF‐4F in cap‐dependent and cap‐independent initiation of translation. A Pause, N Methot, Y Svitkin, WC Merrick, N Sonenberg The EMBO journal 13 (5), 1205-1215, 1994 | 491 | 1994 |
| The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis A Pause, N Méthot, N Sonenberg Molecular and cellular biology 13 (11), 6789-6798, 1993 | 394 | 1993 |
| An oxygen-regulated switch in the protein synthesis machinery J Uniacke, CE Holterman, G Lachance, A Franovic, MD Jacob, MR Fabian, ... Nature 486 (7401), 126-129, 2012 | 357 | 2012 |
| Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus. AC Gingras, Y Svitkin, GJ Belsham, A Pause, N Sonenberg Proceedings of the National Academy of Sciences 93 (11), 5578-5583, 1996 | 323 | 1996 |
| Hepatitis C therapeutics: current status and emerging strategies SL Tan, A Pause, Y Shi, N Sonenberg Nature Reviews Drug Discovery 1 (11), 867-881, 2002 | 315 | 2002 |
| The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth D Rousseau, AC Gingras, A Pause, N Sonenberg Oncogene 13 (11), 2415-2420, 1996 | 313 | 1996 |
| mTOR pathways in cancer and autophagy M Paquette, L El-Houjeiri, A Pause Cancers 10 (1), 18, 2018 | 312 | 2018 |
| The von Hippel–Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal A Pause, S Lee, KM Lonergan, RD Klausner Proceedings of the National Academy of Sciences 95 (3), 993-998, 1998 | 312 | 1998 |
