12-Lipoxygenase regulates cold adaptation and glucose metabolism by producing the omega-3 lipid 12-HEPE from brown fat LO Leiria, CH Wang, MD Lynes, K Yang, F Shamsi, M Sato, S Sugimoto, ... Cell metabolism 30 (4), 768-783. e7, 2019 | 167 | 2019 |
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice CH Wang, M Lundh, A Fu, R Kriszt, TL Huang, MD Lynes, LO Leiria, ... Science translational medicine 12 (558), eaaz8664, 2020 | 114 | 2020 |
GH and ageing: Pitfalls and new insights A Bartke, J Darcy Best Practice & Research Clinical Endocrinology & Metabolism 31 (1), 113-125, 2017 | 78 | 2017 |
Longevity is impacted by growth hormone action during early postnatal period LY Sun, Y Fang, A Patki, JJE Koopman, DB Allison, CM Hill, ... Elife 6, e24059, 2017 | 65 | 2017 |
Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation S Sugimoto, HA Mena, BE Sansbury, S Kobayashi, T Tsuji, CH Wang, ... Nature metabolism 4 (6), 775-790, 2022 | 59 | 2022 |
Brown adipose tissue function is enhanced in long-lived, male Ames dwarf mice J Darcy, S McFadden, Y Fang, JA Huber, C Zhang, LY Sun, A Bartke Endocrinology 157 (12), 4744-4753, 2016 | 58 | 2016 |
ComBATing aging—does increased brown adipose tissue activity confer longevity? J Darcy, YH Tseng Geroscience 41 (3), 285-296, 2019 | 54 | 2019 |
Effects of rapamycin on growth hormone receptor knockout mice Y Fang, CM Hill, J Darcy, A Reyes-Ordoñez, E Arauz, S McFadden, ... Proceedings of the National Academy of Sciences 115 (7), E1495-E1503, 2018 | 49 | 2018 |
Energy metabolism and aging A Bartke, S Brannan, E Hascup, K Hascup, J Darcy The World Journal of Men's Health 39 (2), 222, 2020 | 38 | 2020 |
Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice Y Fang, S McFadden, J Darcy, CM Hill, JA Huber, S Verhulst, JJ Kopchick, ... Geroscience 39, 347-356, 2017 | 27 | 2017 |
17α-Estradiol modulates IGF1 and hepatic gene expression in a sex-specific manner S Sidhom, A Schneider, Y Fang, S McFadden, J Darcy, R Sathiaseelan, ... The Journals of Gerontology: Series A 76 (5), 778-785, 2021 | 25 | 2021 |
Functionally enhanced brown adipose tissue in Ames dwarf mice J Darcy, A Bartke Adipocyte 6 (1), 62-67, 2017 | 23 | 2017 |
Dwarf mice and aging MM Masternak, J Darcy, B Victoria, A Bartke Progress in molecular biology and translational science 155, 69-83, 2018 | 22 | 2018 |
Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity J Darcy, Y Fang, S McFadden, MD Lynes, LO Leiria, JM Dreyfuss, ... Geroscience 42, 1527-1546, 2020 | 21 | 2020 |
Impact of serum proteins on the uptake and RNAi activity of GalNAc-conjugated siRNAs S Agarwal, R Allard, J Darcy, S Chigas, Y Gu, T Nguyen, S Bond, ... nucleic acid therapeutics 31 (4), 309-315, 2021 | 20 | 2021 |
Altered structure and function of adipose tissue in long-lived mice with growth hormone-related mutations J Darcy, S McFadden, A Bartke Adipocyte 6 (2), 69-75, 2017 | 18 | 2017 |
Lifespan of long‐lived growth hormone receptor knockout mice was not normalized by housing at 30° C since weaning Y Fang, S McFadden, J Darcy, ER Hascup, KN Hascup, A Bartke Aging Cell 19 (5), e13123, 2020 | 14 | 2020 |
Increased environmental temperature normalizes energy metabolism outputs between normal and Ames dwarf mice J Darcy, S McFadden, Y Fang, DE Berryman, EO List, N Milcik, A Bartke Aging (Albany NY) 10 (10), 2709, 2018 | 13 | 2018 |
Metabolic alterations from early life thyroxine replacement therapy in male Ames dwarf mice are transient J Darcy, Y Fang, CM Hill, S McFadden, LY Sun, A Bartke Experimental Biology and Medicine 241 (16), 1764-1771, 2016 | 11 | 2016 |
The link between stress and IL-6 is heating up J Darcy, YH Tseng Cell metabolism 32 (2), 152-153, 2020 | 9 | 2020 |