Parin Shah
Parin Shah
Harvard University, DFCI, MD Anderson Cancer Center
在 的電子郵件地址已通過驗證
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ...
Science 352 (6282), 189-196, 2016
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state
M Fallahi‐Sichani, V Becker, B Izar, GJ Baker, JR Lin, SA Boswell, P Shah, ...
Molecular systems biology 13 (1), 2017
Ex vivo profiling of PD-1 blockade using organotypic tumor spheroids
RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ...
Cancer Discovery 8 (2), 196-215, 2018
A simple open-source method for highly multiplexed imaging of single cells in tissues and tumours
JR Lin, B Izar, S Mei, S Wang, P Shah, PK Sorger
elife, 2018
Combination wt-p53 and MicroRNA-125b transfection in a genetically engineered lung cancer model using dual CD44/EGFR-targeting nanoparticles
M Talekar, M Trivedi, P Shah, Q Ouyang, A Oka, S Gandham, MM Amiji
Molecular Therapy 24 (4), 759-769, 2016
Modification of tumor cell exosome content by transfection with wt-p53 and microRNA-125b expressing plasmid DNA and its effect on macrophage polarization
M Trivedi, M Talekar, P Shah, Q Ouyang, M Amiji
Oncogenesis 5 (8), e250-e250, 2016
Bidirectional cross talk between patient‐derived melanoma and cancer‐associated fibroblasts promotes invasion and proliferation
B Izar, CE Joyce, S Goff, NL Cho, PM Shah, G Sharma, J Li, N Ibrahim, ...
Pigment cell & melanoma research 29 (6), 656-668, 2016
MicroRNA-34a encapsulated in hyaluronic acid nanoparticles induces epigenetic changes with altered mitochondrial bioenergetics and apoptosis in non-small-cell lung cancer cells
M Trivedi, A Singh, M Talekar, G Pawar, P Shah, M Amiji
Scientific reports 7 (1), 1-17, 2017
Widespread expression of GDNF throughout rat brain after intranasal delivery of hGDNF plasmid nanoparticles
AEE Aly, BT Harmon, P Shah, O Sesenoglu-Laird, L Padegimas, ...
CELL TRANSPLANTATION 24 (4), 752-753, 2015
Single-cell RNA-sequencing and-imaging of melanoma ecosystems reveals sources of resistance to immune checkpoint blockade.
B Izar, L Jerby-Arnon, A Rotem, P Shah, D Liu, G Zhang, B Schilling, ...
Journal of Clinical Oncology 36 (15_suppl), 3074-3074, 2018
Abstract AP19: single–cell rna–sequencing of patient–derived ovarian cancer cells and patient–derived xenograft models
B Izar, E Stover, I Tirosh, A Rotem, P Shah, C Rodman, S Prakadan, ...
Clinical Cancer Research 23 (11 Supplement), AP19-AP19, 2017
Dissecting treatment resistance in patients with ovarian cancer and PDX-models using single-cell RNA-sequencing
B Izar, I Tirosh, E Stover, A Rotem, P Shah, M Cuoco, C Rodman, J Liu, ...
Cancer Research 77 (13 Supplement), 3037-3037, 2017
Abstract SY45-04: Development of therapeutic strategies by resolving the tumor ecosystem
B Izar, L Jerby-Arnon, I Tirosh, P Shah, MC Cuoco, C Rodman, MJ Su, ...
Cancer Research 79 (13 Supplement), SY45-04-SY45-04, 2019
Abstract A082: Single-cell RNA-sequencing of metastatic melanoma identifies a cancer cell-intrinsic program associated with immune checkpoint inhibitor resistance
L Jerby, P Shah, MS Cuoco, C Rodman, MJ Su, JM Melms, R Leeson, ...
Cancer Immunology Research 7 (2 Supplement), A082-A082, 2019
Long-chain acyl-CoA synthetase 1 role in sepsis and immunity: perspectives from a parallel review of public transcriptome datasets and of the literature.
J Roelands, M Garand, EM Hinchcliff, Y Ma, P Shah, M Toufiq, M Alfaki, ...
Frontiers in immunology 10, 2410, 2019
A cancer precision medicine platform for multiple simultaneous genomic assays from metastatic biopsies (bx) in ER+ metastatic breast cancer.
N Wagle, K Helvie, MR Lloyd, L Marini, AG Waks, O Cohen, C Oh, ...
Journal of Clinical Oncology 34 (15_suppl), 11513-11513, 2016
Implementation of single-cell genomics as a translational tool in patients with metastatic melanoma.
B Izar, I Tirosh, S Prakadan, M Wadsworth, A Rotem, J Trombetta, P Shah, ...
Journal of Clinical Oncology 34 (15_suppl), 11503-11503, 2016
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
MH Wadsworth II, D Treacy, JJ Trombetta, A Rotem, C Rodman, C Lian, ...
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