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Yu-An Chen
Yu-An Chen
Harvard Medical School; University of Texas at Austin
Verified email at hms.harvard.edu
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Year
The Human Tumor Atlas Network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
2002020
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ...
Nature communications 11 (1), 1-13, 2020
1172020
A complementary palette of NanoCluster Beacons
JM Obliosca, MC Babin, C Liu, YL Liu, YA Chen, RA Batson, M Ganguly, ...
ACS nano 8 (10), 10150-10160, 2014
762014
Assessing metastatic potential of breast cancer cells based on EGFR dynamics
YL Liu, CK Chou, M Kim, R Vasisht, YA Kuo, P Ang, C Liu, EP Perillo, ...
Scientific reports 9 (1), 1-13, 2019
412019
NanoCluster Beacons Enable Detection of a Single N6-Methyladenine
YA Chen, JM Obliosca, YL Liu, C Liu, ML Gwozdz, HC Yeh
Journal of the American Chemical Society 137 (33), 10476-10479, 2015
412015
Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer
R Rashid, G Gaglia, YA Chen, JR Lin, Z Du, Z Maliga, D Schapiro, C Yapp, ...
Scientific Data 6 (1), 1-10, 2019
362019
MCMICRO: A scalable, modular image-processing pipeline for multiplexed tissue imaging
D Schapiro, A Sokolov, C Yapp, YA Chen, JL Muhlich, J Hess, ...
Nature methods 19 (3), 311-315, 2022
302022
NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection
S Juul, JM Obliosca, C Liu, YL Liu, YA Chen, DM Imphean, BR Knudsen, ...
Nanoscale 7 (18), 8332-8337, 2015
292015
3D single-molecule tracking enables direct hybridization kinetics measurement in solution
C Liu, JM Obliosca, YL Liu, YA Chen, N Jiang, HC Yeh
Nanoscale 9 (17), 5664-5670, 2017
202017
Evolution of delayed resistance to immunotherapy in a melanoma responder
D Liu, JR Lin, EJ Robitschek, GG Kasumova, A Heyde, A Shi, A Kraya, ...
Nature medicine 27 (6), 985-992, 2021
142021
LNA thymidine monomer enables differentiation of the four single-nucleotide variants by melting temperature
JM Obliosca, SY Cheng, YA Chen, MF Llanos, YL Liu, DM Imphean, ...
Journal of the American Chemical Society 139 (20), 7110-7116, 2017
142017
MITI minimum information guidelines for highly multiplexed tissue images
D Schapiro, C Yapp, A Sokolov, SM Reynolds, YA Chen, D Sudar, Y Xie, ...
Nature methods 19 (3), 262-267, 2022
132022
The spatial landscape of progression and immunoediting in primary melanoma at single cell resolution
AJ Nirmal, Z Maliga, T Vallius, B Quattrochi, AA Chen, CA Jacobson, ...
Cancer discovery 12 (6), 1518, 2022
112022
Multiplexed 3D atlas of state transitions and immune interactions in colorectal cancer
JR Lin, S Wang, S Coy, MA Tyler, C Yapp, YA Chen, CN Heiser, K Lau, ...
bioRxiv, 2021
112021
Improving NanoCluster Beacon performance by blocking the unlabeled NC probes
YA Chen, HT Vu, YL Liu, YI Chen, TD Nguyen, YA Kuo, S Hong, YA Chen, ...
Chemical communications 55 (4), 462-465, 2019
112019
Stitching and registering highly multiplexed whole slide images of tissues and tumors using ASHLAR software
JL Muhlich, YA Chen, DPW Russell, PK Sorger
bioRxiv, 2021
92021
Minerva: a light-weight, narrative image browser for multiplexed tissue images
J Hoffer, R Rashid, JL Muhlich, YA Chen, DPW Russell, J Ruokonen, ...
Journal of open source software 5 (54), 2020
92020
UnMICST: Deep learning with real augmentation for robust segmentation of highly multiplexed images of human tissues
C Yapp, E Novikov, WD Jang, YA Chen, M Cicconet, Z Maliga, ...
bioRxiv, 2021
72021
Three-Dimensional Two-Color Dual-Particle Tracking Microscope for Monitoring DNA Conformational Changes and Nanoparticle Landings on Live Cells
YL Liu, EP Perillo, P Ang, M Kim, DT Nguyen, K Blocher, YA Chen, C Liu, ...
ACS nano 14 (7), 7927-7939, 2020
72020
Online narrative guides for illuminating tissue atlas data and digital pathology images
R Rashid, YA Chen, J Hoffer, JL Muhlich, JR Lin, R Krueger, H Pfister, ...
bioRxiv, 2020
52020
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