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Sachin G. Thakkar
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Lipid nanoparticles with minimum burst release of TNF-α siRNA show strong activity against rheumatoid arthritis unresponsive to methotrexate
AM Aldayel, HL O'Mary, SA Valdes, X Li, SG Thakkar, BE Mustafa, Z Cui
Journal of Controlled Release 283, 280-289, 2018
982018
A method of lyophilizing vaccines containing aluminum salts into a dry powder without causing particle aggregation or decreasing the immunogenicity following reconstitution …
X Li, SG Thakkar, TB Ruwona, RO Williams III, Z Cui
JOURNAL OF CONTROLLED RELEASE 209, 197-197, 2015
55*2015
Intranasal immunization with aluminum salt-adjuvanted dry powder vaccine
SG Thakkar, ZN Warnken, RF Alzhrani, SA Valdes, AM Aldayel, H Xu, ...
Journal of controlled release 292, 111-118, 2018
462018
Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results
A Heczey, X Xu, AN Courtney, G Tian, GA Barragan, L Guo, CM Amador, ...
Nature Medicine 29 (6), 1379-1388, 2023
442023
Aluminum (oxy) hydroxide nanosticks synthesized in bicontinuous reverse microemulsion have potent vaccine adjuvant activity
X Li, S Hufnagel, H Xu, SA Valdes, SG Thakkar, Z Cui, H Celio
ACS applied materials & interfaces 9 (27), 22893-22901, 2017
442017
Feasibility and preclinical efficacy of CD7-unedited CD7 CAR T cells for T cell malignancies
N Watanabe, F Mo, R Zheng, R Ma, VC Bray, DG van Leeuwen, ...
Molecular Therapy 31 (1), 24-34, 2023
342023
The immunogenicity of thin-film freeze-dried, aluminum salt-adjuvanted vaccine when exposed to different temperatures
SG Thakkar, TB Ruwona, RO Williams III, Z Cui
Human vaccines & immunotherapeutics 13 (4), 936-946, 2017
262017
A solid lipid nanoparticle formulation of 4-(N)-docosahexaenoyl 2′, 2′-difluorodeoxycytidine with increased solubility, stability, and antitumor activity
SA Valdes, RF Alzhrani, A Rodriguez, DSP Lansakara-P, SG Thakkar, ...
International journal of pharmaceutics 570, 118609, 2019
252019
Uric acid and the vaccine adjuvant activity of aluminium (oxy) hydroxide nanoparticles
SG Thakkar, H Xu, X Li, Z Cui
Journal of drug targeting 26 (5-6), 474-480, 2018
192018
Nasal aluminum (oxy) hydroxide enables adsorbed antigens to induce specific systemic and mucosal immune responses
H Xu, TB Ruwona, SG Thakkar, Y Chen, M Zeng, Z Cui
Human vaccines & immunotherapeutics 13 (11), 2688-2694, 2017
172017
Immunogenicity of antigen adjuvanted with AS04 and its deposition in the upper respiratory tract after intranasal administration
H Xu, RF Alzhrani, ZN Warnken, SG Thakkar, M Zeng, HDC Smyth, ...
Molecular Pharmaceutics 17 (9), 3259-3269, 2020
112020
Amorphous or crystalline? A comparison of particle engineering methods and selection
SG Thakkar, K Fathe, H DC Smyth
Current pharmaceutical design 21 (40), 5789-5801, 2015
112015
CD30. CAR-modified Epstein-Barr virus-specific T cells (CD30. CAR EBVSTs) provide a safe and effective off-the-shelf therapy for patients with CD30-positive lymphoma
DH Quach, CA Ramos, PD Lulla, S Sharma, HR Ganesh, N Nouraee, ...
Blood 140 (Supplement 1), 412-414, 2022
102022
Methods to prepare aluminum salt-adjuvanted vaccines
SG Thakkar, Z Cui
Vaccine Adjuvants: Methods and Protocols, 181-199, 2017
102017
OFF‐THE‐SHELF CD30. CAR‐MODIFIED EPSTEIN‐BARR VIRUS‐SPECIFIC T CELLS (CD30. CAR EBVSTS) PROVIDE A SAFE AND EFFECTIVE THERAPY FOR PATIENTS WITH HODGKIN LYMPHOMA (HL)
CA Ramos, DH Quach, PD Lulla, RH Rouce, S Sharma, HR Ganesh, ...
Hematological Oncology 41, 83-85, 2023
72023
Safety and efficacy of off-the-shelf cd30. car-modified epstein-barr virus-specific t cells in patients with cd30-positive lymphoma
DH Quach, CA Ramos, PD Lulla, S Sharma, HR Ganesh, YF Hadidi, ...
Blood 138, 1763, 2021
72021
A Bank of CD30.CAR-Modified, Epstein-Barr Virus-Specific T Cells That Lacks Host Reactivity and Resists Graft Rejection for Patients with CD30-Positive Lymphoma
DH Quach, HR Ganesh, SG Thakkar, L Becerra-Dominguez, B Mehta, ...
Blood, 62nd ASH Annual Meeting & Exposition 136 (1), 16, 2020
62020
Toll-deficient Drosophila are resistant to infection by Pneumocystis spp.: additional evidence of specificity to mammalian hosts
SE Evans, K Leventakos, R Ben-Ami, D You, SG Thakkar, RE Lewis, ...
Virulence 1 (6), 523-525, 2010
62010
Enhanced anti-tumor activity of CD5 CAR T cells manufactured with tyrosine kinase inhibitors in patients with relapsed/refractory T-ALL.
LQC Hill, RH Rouce, TS Smith, B Boriskie, M Srinivasan, SG Thakkar, ...
Journal of Clinical Oncology 41 (16_suppl), 7002-7002, 2023
52023
Anti-GD2 CAR NKT cells are safe and produce antitumor responses in patients with relapsed/refractory neuroblastoma
A Heczey, A Courtney, N Ghatwai, S Thakkar, P Rathi, X Xu, H Ngai, ...
Mol Ther 30 (4 suppl 1), 28, 2022
22022
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