Zoltan Maliga
Zoltan Maliga
Laboratory of Systems Pharmacology, Harvard Medical School
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SARS-CoV-2 infection protects against rechallenge in rhesus macaques
A Chandrashekar, J Liu, AJ Martinot, K McMahan, NB Mercado, L Peter, ...
Science 369 (6505), 812-817, 2020
Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5
Z Maliga, TM Kapoor, TJ Mitchison
Chemistry & biology 9 (9), 989-996, 2002
Hydrolysis of 2′ 3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs
L Li, Q Yin, P Kuss, Z Maliga, JL Millán, H Wu, TJ Mitchison
Nature chemical biology 10 (12), 1043-1048, 2014
A protein domain-based interactome network for C. elegans early embryogenesis
M Boxem, Z Maliga, N Klitgord, N Li, I Lemmens, M Mana, ...
Cell 134 (3), 534-545, 2008
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
Obesity shapes metabolism in the tumor microenvironment to suppress anti-tumor immunity
AE Ringel, JM Drijvers, GJ Baker, A Catozzi, JC García-Cañaveras, ...
Cell 183 (7), 1848-1866. e26, 2020
Vascular disease and thrombosis in SARS-CoV-2-infected rhesus macaques
M Aid, K Busman-Sahay, SJ Vidal, Z Maliga, S Bondoc, C Starke, M Terry, ...
Cell 183 (5), 1354-1366. e13, 2020
Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour
AW Ettinger, M Wilsch-Bräuninger, AM Marzesco, M Bickle, A Lohmann, ...
Nature communications 2 (1), 1-12, 2011
Natural product–inspired cascade synthesis yields modulators of centrosome integrity
H Dückert, V Pries, V Khedkar, S Menninger, H Bruss, AW Bird, Z Maliga, ...
Nature chemical biology 8 (2), 179-184, 2012
A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A
J Stumpff, Y Du, CA English, Z Maliga, M Wagenbach, CL Asbury, ...
Molecular cell 43 (5), 764-775, 2011
Anticancer flavonoids are mouse-selective STING agonists
S Kim, L Li, Z Maliga, Q Yin, H Wu, TJ Mitchison
ACS chemical biology 8 (7), 1396-1401, 2013
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ...
Nature communications 11 (1), 1-13, 2020
Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux
S Maffini, ARR Maia, AL Manning, Z Maliga, AL Pereira, M Junqueira, ...
Current Biology 19 (18), 1566-1572, 2009
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation
VG Magupalli, R Negro, Y Tian, AV Hauenstein, G Di Caprio, W Skillern, ...
Science 369 (6510), eaas8995, 2020
Phase transitions drive the formation of vesicular stomatitis virus replication compartments
BS Heinrich, Z Maliga, DA Stein, AA Hyman, SPJ Whelan
MBio 9 (5), e02290-17, 2018
Mechanistic analysis of the mitotic kinesin Eg5
JC Cochran, CA Sontag, Z Maliga, TM Kapoor, JJ Correia, SP Gilbert
Journal of Biological Chemistry 279 (37), 38861-38870, 2004
Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol
Z Maliga, TJ Mitchison
BMC chemical biology 6 (1), 1-9, 2006
A genomic toolkit to investigate kinesin and myosin motor function in cells
Z Maliga, M Junqueira, Y Toyoda, A Ettinger, F Mora-Bermúdez, ...
Nature cell biology 15 (3), 325-334, 2013
Cross-inhibition of SR-BI-and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide
TJF Nieland, A Chroni, ML Fitzgerald, Z Maliga, VI Zannis, T Kirchhausen, ...
Journal of lipid research 45 (7), 1256-1265, 2004
Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein
A Dauber, SH LaFranchi, Z Maliga, JC Lui, JE Moon, C McDeed, K Henke, ...
The Journal of Clinical Endocrinology & Metabolism 97 (11), E2140-E2151, 2012
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