Tomoko Obara
Tomoko Obara
University of Oklahoma Health Science Center
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Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
M Simons, J Gloy, A Ganner, A Bullerkotte, M Bashkurov, C Krönig, ...
Nature genetics 37 (5), 537-543, 2005
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
EA Otto, B Schermer, T Obara, JF O'Toole, KS Hiller, AM Mueller, RG Ruf, ...
Nature genetics 34 (4), 413-420, 2003
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease
SH Low, S Vasanth, CH Larson, S Mukherjee, N Sharma, MT Kinter, ...
Developmental cell 10 (1), 57-69, 2006
FGF-7 modulates ureteric bud growth and nephron number in the developing kidney
J Qiao, R Uzzo, T Obara-Ishihara, L Degenstein, E Fuchs, D Herzlinger
Development 126 (3), 547-554, 1999
Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions
M Nakafuku, T Obara, K Kaibuchi, I Miyajima, A Miyajima, H Itoh, ...
Proceedings of the National Academy of Sciences 85 (5), 1374-1378, 1988
roundabout4 is essential for angiogenesis in vivo
VM Bedell, SY Yeo, KW Park, J Chung, P Seth, V Shivalingappa, J Zhao, ...
Proceedings of the National Academy of Sciences 102 (18), 6373-6378, 2005
Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry
S Kim, NA Zaghloul, E Bubenshchikova, EC Oh, S Rankin, N Katsanis, ...
Nature cell biology 13 (4), 351-360, 2011
A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish
S Liu, W Lu, T Obara, S Kuida, J Lehoczky, K Dewar, IA Drummond, ...
Oxford University Press for The Company of Biologists Limited 129 (24), 5839 …, 2002
The Zebrafish fleer Gene Encodes an Essential Regulator of Cilia Tubulin Polyglutamylation
N Pathak, T Obara, S Mangos, Y Liu, IA Drummond
Molecular biology of the cell 18 (11), 4353-4364, 2007
Isolation and characterization of a gene encoding a G-protein alpha subunit from Schizosaccharomyces pombe: involvement in mating and sporulation pathways.
T Obara, M Nakafuku, M Yamamoto, Y Kaziro
Proceedings of the National Academy of Sciences 88 (13), 5877-5881, 1991
The surface ectoderm is essential for nephric duct formation in intermediate mesoderm
T Obara-Ishihara, J Kuhlman, L Niswander, D Herzlinger
Development 126 (6), 1103-1108, 1999
AB‐type cyclin negatively regulates conjugation via interacting with cell cycle ‘start’genes in fission yeast.
T Obara‐Ishihara, H Okayama
The EMBO Journal 13 (8), 1863-1872, 1994
Polycystin-2 immunolocalization and function in zebrafish
T Obara, S Mangos, Y Liu, J Zhao, S Wiessner, AG Kramer-Zucker, ...
Journal of the American Society of Nephrology 17 (10), 2706-2718, 2006
Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro
AJ Streets, DJ Moon, ME Kane, T Obara, ACM Ong
Human molecular genetics 15 (9), 1465-1473, 2006
A polycystin‐2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes
A Giamarchi, S Feng, L Rodat‐Despoix, Y Xu, E Bubenshchikova, ...
The EMBO journal 29 (7), 1176-1191, 2010
Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2
S Feng, GM Okenka, CX Bai, AJ Streets, LJ Newby, BT DeChant, ...
Journal of Biological Chemistry 283 (42), 28471-28479, 2008
Fish and frogs: models for vertebrate cilia signaling
O Wessely, T Obara
Frontiers in bioscience: a journal and virtual library 13, 1866, 2008
Nephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros
Y Fukuyo, T Nakamura, E Bubenshchikova, R Powell, T Tsuji, ...
Molecular medicine reports 9 (2), 457-465, 2014
Structures of the Genes Coding for G-protein a Subunits from Mammalian and Yeast Cells
Y Kaziro, H Itoh, T Kozasa, R Toyama, T Tsukamoto, M Matsuoka, ...
Cold Spring Harbor symposia on quantitative biology 53, 209-220, 1988
Medaka fish, Oryzias latipes, as a model for human obesity-related glomerulopathy
K Ichimura, Y Kawashima, T Nakamura, R Powell, Y Hidoh, S Terai, ...
Biochemical and biophysical research communications 431 (4), 712-717, 2013
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