Jan-Ake Gustafsson

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Jan Carlstedt-DukeSenior Advisor (Medicine), Nanyang Technological University, SingaporeVerified email at ntu.edu.sg
Anders StromResearch Associate Professor, University of HoustonVerified email at uh.edu
claes.ohlsson@medic.gu.seProfessor, Göteborgs Universitet, Sahlgrenska Akademin, SwedenVerified email at medic.gu.se
Tomas HökfeltSenior professor, Karolinska InstitutetVerified email at ki.se
Olle KämpeTorsten and Ragnar Söderberg professor of Clinical Endocrinology, Karolinska InstitutetVerified email at ki.se
Ashley PikeCentre for Medicines Discovery - University of OxfordVerified email at cmd.ox.ac.uk
Maria BondessonIndiana UniversityVerified email at iu.edu
Magnus Ingelman-SundbergKarolinska InstitutetVerified email at ki.se
Cecilia WilliamsProfessor at KTH, Karolinska InstitutetVerified email at scilifelab.se
Roderick HubbardUniversity of York and Vernalis (R&D) LtdVerified email at york.ac.uk
Johan HartmanDept of Oncology-Pathology, Karolinska InstitutetVerified email at ki.se
Bart van der BurgDirector of Innovation, BioDetection Systems BV, AmsterdamVerified email at bds.nl
Torleif HärdProfessor of Structural Molecular Biology, SLU, UppsalaVerified email at slu.se
luisa helgueroDep of Chemistry, University of AveiroVerified email at ua.pt
Bo AngelinKarolinska InstitutetVerified email at ki.se
Iain J McEwanProfessor, University of Aberdeen, UKVerified email at abdn.ac.uk
Edward T. MorganEmory UniversityVerified email at emory.edu

Jan-Ake Gustafsson

Robert A. Welch Professor, Department of Biology and Biochemistry, University of Houston

Verified email at central.uh.edu - Homepage

estrogen receptors ER-beta ER-beta agonist is being developed against prostate cancer


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Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β GGJM Kuiper, BO Carlsson, KAJ Grandien, E Enmark, J Häggblad, ... Endocrinology 138 (3), 863-870, 1997	6038	1997
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β GGJM Kuiper, JG Lemmen, BO Carlsson, JC Corton, SH Safe, ... Endocrinology 139 (10), 4252-4263, 1998	5557	1998
Molecular basis of agonism and antagonism in the oestrogen receptor AM Brzozowski, ACW Pike, Z Dauter, RE Hubbard, T Bonn, O Engström, ... Nature 389 (6652), 753-758, 1997	4190	1997
Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites K Paech, P Webb, GGJM Kuiper, S Nilsson, JÅ Gustafsson, PJ Kushner, ... Science 277 (5331), 1508-1510, 1997	3117	1997
Mechanisms of estrogen action S Nilsson, S Makela, E Treuter, M Tujague, J Thomsen, G Andersson, ... Physiological reviews 81 (4), 1535-1565, 2001	2727	2001
Estrogen receptors: how do they signal and what are their targets N Heldring, A Pike, S Andersson, J Matthews, G Cheng, J Hartman, ... Physiological reviews 87 (3), 905-931, 2007	2343	2007
Generation and reproductive phenotypes of mice lacking estrogen receptor β JH Krege, JB Hodgin, JF Couse, E Enmark, M Warner, JF Mahler, M Sar, ... Proceedings of the National Academy of Sciences 95 (26), 15677-15682, 1998	2167	1998
Human estrogen receptor β-gene structure, chromosomal localization, and expression pattern E Enmark, M Pelto-Huikko, KAJ Grandien, S Lagercrantz, J Lagercrantz, ... The Journal of Clinical Endocrinology & Metabolism 82 (12), 4258-4265, 1997	1852	1997
Principles for modulation of the nuclear receptor superfamily H Gronemeyer, JÅ Gustafsson, V Laudet Nature reviews Drug discovery 3 (11), 950-964, 2004	1544	2004
Structure of the ligand‐binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist ACW Pike, AM Brzozowski, RE Hubbard, T Bonn, AG Thorsell, ... The EMBO journal, 1999	1302	1999
Tissue distribution and quantitative analysis of estrogen receptor-α (ERα) and estrogen receptor-β (ERβ) messenger ribonucleic acid in the wild-type and ERα-knockout mouse JF Couse, J Lindzey, KAJ Grandien, JA Gustafsson, KS Korach Endocrinology 138 (11), 4613-4621, 1997	1292	1997
A unified nomenclature system for the nuclear receptor superfamily J Auwerx, E Baulieu, M Beato, M Becker-Andre, PH Burbach, G Camerino, ... Cell 97 (2), 161-163, 1999	1184	1999
Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. M Göttlicher, E Widmark, Q Li, JA Gustafsson Proceedings of the National Academy of Sciences 89 (10), 4653-4657, 1992	1145	1992
Estrogen signaling: a subtle balance between ERα and ERβ J Matthews, JÅ Gustafsson Molecular interventions 3 (5), 281, 2003	1118	2003
Differential response of estrogen receptor α and estrogen receptor β to partial estrogen agonists/antagonists T Barkhem, BO Carlsson, Y Nilsson, E Enmark, JÅ Gustafsson, S Nilsson Molecular pharmacology 54 (1), 105-112, 1998	1109	1998
Mouse estrogen receptor β forms estrogen response element-binding heterodimers with estrogen receptor α K Pettersson, K Grandien, GGJM Kuiper, JA Gustafsson Molecular endocrinology 11 (10), 1486-1496, 1997	847	1997
International union of pharmacology. LXIV. Estrogen receptors K Dahlman-Wright, V Cavailles, SA Fuqua, VC Jordan, ... Pharmacological reviews 58 (4), 773-781, 2006	833	2006
Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA R Miesfeld, S Rusconi, PJ Godowski, BA Maler, S Okret, AC Wikström, ... Cell 46 (3), 389-399, 1986	813	1986
The different roles of ER subtypes in cancer biology and therapy C Thomas, JÅ Gustafsson Nature Reviews Cancer 11 (8), 597-608, 2011	812	2011
Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region F Payvar, D DeFranco, GL Firestone, B Edgar, Ö Wrange, S Okret, ... Cell 35 (2), 381-392, 1983	786	1983

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