| sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance A Kaur, MR Webster, K Marchbank, R Behera, A Ndoye, CH Kugel, ... Nature 532 (7598), 250-254, 2016 | 353 | 2016 |
| Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility A Kaur, BL Ecker, SM Douglass, CH Kugel III, MR Webster, FV Almeida, ... Cancer discovery 9 (1), 64-81, 2019 | 299 | 2019 |
| Age correlates with response to anti-PD1, reflecting age-related differences in intratumoral effector and regulatory T-cell populations CH Kugel III, SM Douglass, MR Webster, A Kaur, Q Liu, X Yin, SA Weiss, ... Clinical Cancer Research 24 (21), 5347-5356, 2018 | 297 | 2018 |
| Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2 MP O'Connell, K Marchbank, MR Webster, AA Valiga, A Kaur, A Vultur, ... Cancer discovery 3 (12), 1378-1393, 2013 | 249 | 2013 |
| PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion MC Caino, JC Ghosh, YC Chae, V Vaira, DB Rivadeneira, A Faversani, ... Proceedings of the National Academy of Sciences 112 (28), 8638-8643, 2015 | 205 | 2015 |
| Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion H Ahmadzadeh, MR Webster, R Behera, AM Jimenez Valencia, D Wirtz, ... Proceedings of the National Academy of Sciences 114 (9), E1617-E1626, 2017 | 189 | 2017 |
| Age-related changes in HAPLN1 increase lymphatic permeability and affect routes of melanoma metastasis BL Ecker, A Kaur, SM Douglass, MR Webster, FV Almeida, GE Marino, ... Cancer discovery 9 (1), 82-95, 2019 | 113 | 2019 |
| Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury M Bourdi, DP Eiras, MP Holt, MR Webster, TP Reilly, KD Welch, LR Pohl Chemical research in toxicology 20 (2), 208-216, 2007 | 98 | 2007 |
| Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells. MR Webster, M Xu, KA Kinzler, A Kaur, J Appleton, MP O’Connell, ... Pigment Cell Melanoma Res. 28 (2), 184-195, 2015 | 95 | 2015 |
| The Wnts of change: How Wnts regulate phenotype switching in melanoma MR Webster, CH Kugel III, AT Weeraratna Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1856 (2), 244-251, 2015 | 89 | 2015 |
| Changes in aged fibroblast lipid metabolism induce age-dependent melanoma cell resistance to targeted therapy via the fatty acid transporter FATP2 GM Alicea, VW Rebecca, AR Goldman, ME Fane, SM Douglass, ... Cancer discovery 10 (9), 1282-1295, 2020 | 88 | 2020 |
| A Wnt-er migration: the confusing role of β-catenin in melanoma metastasis MR Webster, AT Weeraratna Science signaling 6 (268), pe11-pe11, 2013 | 88 | 2013 |
| Stromal changes in the aged lung induce an emergence from melanoma dormancy ME Fane, Y Chhabra, GM Alicea, DA Maranto, SM Douglass, MR Webster, ... Nature 606 (7913), 396-405, 2022 | 81 | 2022 |
| In the Wnt-er of life: Wnt signalling in melanoma and ageing A Kaur, MR Webster, AT Weeraratna British journal of cancer 115 (11), 1273-1279, 2016 | 65 | 2016 |
| Novel protein kinase C-mediated control of Orai1 function in invasive melanoma R Hooper, X Zhang, M Webster, C Go, J Kedra, K Marchbank, DL Gill, ... Molecular and cellular biology 35 (16), 2790-2798, 2015 | 61 | 2015 |
| Paradoxical role for wild-type p53 in driving therapy resistance in melanoma MR Webster, ME Fane, GM Alicea, S Basu, AV Kossenkov, GE Marino, ... Molecular cell 77 (3), 633-644. e5, 2020 | 60 | 2020 |
| Metabolism of N, N′, N ″-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms E Harleton, M Webster, NN Bumpus, UM Kent, JM Rae, PF Hollenberg Journal of Pharmacology and Experimental Therapeutics 310 (3), 1011-1019, 2004 | 39 | 2004 |
| Inhibition of age-related therapy resistance in melanoma by rosiglitazone-mediated induction of Klotho R Behera, A Kaur, MR Webster, S Kim, A Ndoye, CH Kugel III, GM Alicea, ... Clinical Cancer Research 23 (12), 3181-3190, 2017 | 38 | 2017 |
| HSP70 inhibition limits FAK-dependent invasion and enhances the response to melanoma treatment with BRAF inhibitors A Budina-Kolomets, MR Webster, JIJ Leu, M Jennis, C Krepler, A Guerrini, ... Cancer research 76 (9), 2720-2730, 2016 | 35 | 2016 |
| Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells MR Webster, M Zhao, MA Rudek, CL Hann, CL Freel Meyers Journal of medicinal chemistry 54 (19), 6647-6656, 2011 | 35 | 2011 |
Xiaowei XuProfessor at University of Pennsylvania, Departments of Pathology and DermatologyVerified email at pennmedicine.upenn.edu
