Splicing factor SF3b as a target of the antitumor natural product pladienolide Y Kotake, K Sagane, T Owa, Y Mimori-Kiyosue, H Shimizu, M Uesugi, ... Nature chemical biology 3 (9), 570-575, 2007 | 692 | 2007 |
Selective degradation of splicing factor CAPERα by anticancer sulfonamides T Uehara, Y Minoshima, K Sagane, NH Sugi, KO Mitsuhashi, ... Nature chemical biology 13 (6), 675-680, 2017 | 316 | 2017 |
Quantitative mouse brain proteomics using culture-derived isotope tags as internal standards Y Ishihama, T Sato, T Tabata, N Miyamoto, K Sagane, T Nagasu, Y Oda Nature biotechnology 23 (5), 617-621, 2005 | 263 | 2005 |
Biological validation that SF3b is a target of the antitumor macrolide pladienolide A Yokoi, Y Kotake, K Takahashi, T Kadowaki, Y Matsumoto, Y Minoshima, ... The FEBS journal 278 (24), 4870-4880, 2011 | 192 | 2011 |
Ataxia and peripheral nerve hypomyelination in ADAM22-deficient mice K Sagane, K Hayakawa, J Kai, T Hirohashi, E Takahashi, N Miyamoto, ... BMC neuroscience 6, 1-12, 2005 | 175 | 2005 |
E1210, a new broad-spectrum antifungal, suppresses Candida albicans hyphal growth through inhibition of glycosylphosphatidylinositol biosynthesis N Watanabe, M Miyazaki, T Horii, K Sagane, K Tsukahara, K Hata Antimicrobial agents and chemotherapy 56 (2), 960-971, 2012 | 146 | 2012 |
Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly K Tsukahara, K Hata, K Nakamoto, K Sagane, N Watanabe, J Kuromitsu, ... Molecular microbiology 48 (4), 1029-1042, 2003 | 133 | 2003 |
Lgi1 and Lgi4 bind to ADAM22, ADAM23 and ADAM11 K Sagane, Y Ishihama, H Sugimoto International journal of biological sciences 4 (6), 387, 2008 | 132 | 2008 |
GWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast M Umemura, M Okamoto, K Nakayama, K Sagane, K Tsukahara, K Hata, ... Journal of Biological Chemistry 278 (26), 23639-23647, 2003 | 130 | 2003 |
Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain K SAGANE, Y OHYA, Y HASEGAWA, I TANAKA Biochemical Journal 334 (1), 93-98, 1998 | 121 | 1998 |
Adam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signaling E Özkaynak, G Abello, M Jaegle, L Van Berge, D Hamer, L Kegel, ... Journal of Neuroscience 30 (10), 3857-3864, 2010 | 100 | 2010 |
Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23 K Sagane, K Yamazaki, Y Mizui, I Tanaka Gene 236 (1), 79-86, 1999 | 82 | 1999 |
Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells Y Shinozuka, M Okada, T Oki, K Sagane, Y Mizui, I Tanaka, K Katayama, ... Biochemical and biophysical research communications 287 (1), 229-235, 2001 | 55 | 2001 |
Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system J Nishino, TL Saunders, K Sagane, SJ Morrison Journal of Neuroscience 30 (45), 15228-15240, 2010 | 51 | 2010 |
Deficits in spatial learning and motor coordination in ADAM11-deficient mice E Takahashi, K Sagane, T Oki, K Yamazaki, T Nagasu, J Kuromitsu BMC neuroscience 7, 1-11, 2006 | 51 | 2006 |
cDNA cloning of mouse tumor necrosis factor-α converting enzyme (TACE) and partial analysis of its promoter Y Mizui, K Yamazaki, K Sagane, I Tanaka Gene 233 (1-2), 67-74, 1999 | 42 | 1999 |
Analysis of membrane topology and identification of essential residues for the yeast endoplasmic reticulum inositol acyltransferase Gwt1p K Sagane, M Umemura, K Ogawa-Mitsuhashi, K Tsukahara, T Yoko-o, ... Journal of Biological Chemistry 286 (16), 14649-14658, 2011 | 38 | 2011 |
Novel antimalarial agent containing heterocyclic compound K Nakamoto, M Matsukura, K Tanaka, S Inoue, I Tsukada, T Haneda, ... US Patent App. 11/658,901, 2009 | 27 | 2009 |
Altered nociceptive response in ADAM11-deficient mice E Takahashi, K Sagane, T Nagasu, J Kuromitsu Brain research 1097 (1), 39-42, 2006 | 27 | 2006 |
Characterization of 5′-flanking region of human aggrecanase-1 (ADAMTS4) gene Y Mizui, K Yamazaki, Y Kuboi, K Sagane, I Tanaka Molecular Biology Reports 27, 167-173, 2000 | 27 | 2000 |