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lingfeng qin
lingfeng qin
Research Scientist, Yale University
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Year
Endothelial-to-mesenchymal transition drives atherosclerosis progression
PY Chen, L Qin, N Baeyens, G Li, T Afolabi, M Budatha, G Tellides, ...
The Journal of clinical investigation 125 (12), 4514-4528, 2015
5362015
FGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression
PY Chen, L Qin, C Barnes, K Charisse, T Yi, X Zhang, R Ali, PP Medina, ...
Cell reports 2 (6), 1684-1696, 2012
3462012
Ten-eleven translocation-2 (TET2) is a master regulator of smooth muscle cell plasticity
R Liu, Y Jin, WH Tang, L Qin, X Zhang, G Tellides, J Hwa, J Yu, KA Martin
Circulation 128 (18), 2047-2057, 2013
3072013
Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis
W Li, Q Li, Y Jiao, L Qin, R Ali, J Zhou, J Ferruzzi, RW Kim, A Geirsson, ...
The Journal of clinical investigation 124 (2), 755-767, 2014
2972014
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis
PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ...
Nature metabolism 1 (9), 912-926, 2019
2572019
Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells
A Misra, Z Feng, RR Chandran, I Kabir, N Rotllan, B Aryal, AQ Sheikh, ...
Nature communications 9 (1), 2073, 2018
1932018
Smooth muscle cell reprogramming in aortic aneurysms
PY Chen, L Qin, G Li, J Malagon-Lopez, Z Wang, S Bergaya, S Gujja, ...
Cell stem cell 26 (4), 542-557. e11, 2020
1802020
Implantable tissue-engineered blood vessels from human induced pluripotent stem cells
L Gui, BC Dash, J Luo, L Qin, L Zhao, K Yamamoto, T Hashimoto, H Wu, ...
Biomaterials 102, 120-129, 2016
1432016
Alloantibody and complement promote T cell–mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells
D Jane-Wit, TD Manes, T Yi, L Qin, P Clark, NC Kirkiles-Smith, P Abrahimi, ...
Circulation 128 (23), 2504-2516, 2013
1412013
Tissue-engineered vascular grafts with advanced mechanical strength from human iPSCs
J Luo, L Qin, L Zhao, L Gui, MW Ellis, Y Huang, MH Kural, JA Clark, S Ono, ...
Cell Stem Cell 26 (2), 251-261. e8, 2020
1362020
Interferon-γ induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase–dependent mammalian target of rapamycin raptor …
Y Wang, Y Bai, L Qin, P Zhang, T Yi, SA Teesdale, L Zhao, JS Pober, ...
Circulation research 101 (6), 560-569, 2007
1352007
Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation
HJ Zhou, L Qin, H Zhang, W Tang, W Ji, Y He, X Liang, Z Wang, Q Yuan, ...
Nature medicine 22 (9), 1033-1042, 2016
124*2016
Interacting mechanisms in the pathogenesis of cardiac allograft vasculopathy
JS Pober, D Jane-Wit, L Qin, G Tellides
Arteriosclerosis, thrombosis, and vascular biology 34 (8), 1609-1614, 2014
1242014
CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses
J Zhou, PCY Tang, L Qin, PM Gayed, W Li, EA Skokos, TR Kyriakides, ...
Journal of Experimental Medicine 207 (9), 1951-1966, 2010
1172010
Fibroblast growth factor receptor 1 is a key inhibitor of TGFβ signaling in the endothelium
PY Chen, L Qin, G Tellides, M Simons
Science signaling 7 (344), ra90-ra90, 2014
1142014
Induction of indoleamine 2, 3-dioxygenase in vascular smooth muscle cells by interferon-γ contributes to medial immunoprivilege
MC Cuffy, AM Silverio, L Qin, Y Wang, R Eid, G Brandacher, FG Lakkis, ...
The Journal of Immunology 179 (8), 5246-5254, 2007
1122007
Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection
DA Rao, RE Eid, L Qin, T Yi, NC Kirkiles-Smith, G Tellides, JS Pober
The Journal of experimental medicine 205 (13), 3145-3158, 2008
1052008
Smooth muscle FGF/TGF β cross talk regulates atherosclerosis progression
PY Chen, L Qin, G Li, G Tellides, M Simons
EMBO molecular medicine 8 (7), 712-728, 2016
972016
Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells
J Cui, L Qin, J Zhang, P Abrahimi, H Li, G Li, GT Tietjen, G Tellides, ...
Nature Communications 8 (1), 191, 2017
962017
Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGFβ)-dependent smooth muscle cell phenotype modulation
PY Chen, L Qin, G Li, G Tellides, M Simons
Scientific reports 6 (1), 33407, 2016
932016
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