Endothelial-to-mesenchymal transition drives atherosclerosis progression PY Chen, L Qin, N Baeyens, G Li, T Afolabi, M Budatha, G Tellides, ... The Journal of clinical investigation 125 (12), 4514-4528, 2015 | 536 | 2015 |
FGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression PY Chen, L Qin, C Barnes, K Charisse, T Yi, X Zhang, R Ali, PP Medina, ... Cell reports 2 (6), 1684-1696, 2012 | 346 | 2012 |
Ten-eleven translocation-2 (TET2) is a master regulator of smooth muscle cell plasticity R Liu, Y Jin, WH Tang, L Qin, X Zhang, G Tellides, J Hwa, J Yu, KA Martin Circulation 128 (18), 2047-2057, 2013 | 307 | 2013 |
Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis W Li, Q Li, Y Jiao, L Qin, R Ali, J Zhou, J Ferruzzi, RW Kim, A Geirsson, ... The Journal of clinical investigation 124 (2), 755-767, 2014 | 297 | 2014 |
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ... Nature metabolism 1 (9), 912-926, 2019 | 257 | 2019 |
Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells A Misra, Z Feng, RR Chandran, I Kabir, N Rotllan, B Aryal, AQ Sheikh, ... Nature communications 9 (1), 2073, 2018 | 193 | 2018 |
Smooth muscle cell reprogramming in aortic aneurysms PY Chen, L Qin, G Li, J Malagon-Lopez, Z Wang, S Bergaya, S Gujja, ... Cell stem cell 26 (4), 542-557. e11, 2020 | 180 | 2020 |
Implantable tissue-engineered blood vessels from human induced pluripotent stem cells L Gui, BC Dash, J Luo, L Qin, L Zhao, K Yamamoto, T Hashimoto, H Wu, ... Biomaterials 102, 120-129, 2016 | 143 | 2016 |
Alloantibody and complement promote T cell–mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells D Jane-Wit, TD Manes, T Yi, L Qin, P Clark, NC Kirkiles-Smith, P Abrahimi, ... Circulation 128 (23), 2504-2516, 2013 | 141 | 2013 |
Tissue-engineered vascular grafts with advanced mechanical strength from human iPSCs J Luo, L Qin, L Zhao, L Gui, MW Ellis, Y Huang, MH Kural, JA Clark, S Ono, ... Cell Stem Cell 26 (2), 251-261. e8, 2020 | 136 | 2020 |
Interferon-γ induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase–dependent mammalian target of rapamycin raptor … Y Wang, Y Bai, L Qin, P Zhang, T Yi, SA Teesdale, L Zhao, JS Pober, ... Circulation research 101 (6), 560-569, 2007 | 135 | 2007 |
Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation HJ Zhou, L Qin, H Zhang, W Tang, W Ji, Y He, X Liang, Z Wang, Q Yuan, ... Nature medicine 22 (9), 1033-1042, 2016 | 124* | 2016 |
Interacting mechanisms in the pathogenesis of cardiac allograft vasculopathy JS Pober, D Jane-Wit, L Qin, G Tellides Arteriosclerosis, thrombosis, and vascular biology 34 (8), 1609-1614, 2014 | 124 | 2014 |
CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses J Zhou, PCY Tang, L Qin, PM Gayed, W Li, EA Skokos, TR Kyriakides, ... Journal of Experimental Medicine 207 (9), 1951-1966, 2010 | 117 | 2010 |
Fibroblast growth factor receptor 1 is a key inhibitor of TGFβ signaling in the endothelium PY Chen, L Qin, G Tellides, M Simons Science signaling 7 (344), ra90-ra90, 2014 | 114 | 2014 |
Induction of indoleamine 2, 3-dioxygenase in vascular smooth muscle cells by interferon-γ contributes to medial immunoprivilege MC Cuffy, AM Silverio, L Qin, Y Wang, R Eid, G Brandacher, FG Lakkis, ... The Journal of Immunology 179 (8), 5246-5254, 2007 | 112 | 2007 |
Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection DA Rao, RE Eid, L Qin, T Yi, NC Kirkiles-Smith, G Tellides, JS Pober The Journal of experimental medicine 205 (13), 3145-3158, 2008 | 105 | 2008 |
Smooth muscle FGF/TGF β cross talk regulates atherosclerosis progression PY Chen, L Qin, G Li, G Tellides, M Simons EMBO molecular medicine 8 (7), 712-728, 2016 | 97 | 2016 |
Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells J Cui, L Qin, J Zhang, P Abrahimi, H Li, G Li, GT Tietjen, G Tellides, ... Nature Communications 8 (1), 191, 2017 | 96 | 2017 |
Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGFβ)-dependent smooth muscle cell phenotype modulation PY Chen, L Qin, G Li, G Tellides, M Simons Scientific reports 6 (1), 33407, 2016 | 93 | 2016 |