Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes B Chapuy, C Stewart, AJ Dunford, J Kim, A Kamburov, RA Redd, ... Nature medicine 24 (5), 679-690, 2018 | 1545 | 2018 |
AACR Project GENIE: powering precision medicine through an international consortium AACR Project Genie Consortium, AACR Project GENIE Consortium, ... Cancer discovery 7 (8), 818-831, 2017 | 1234 | 2017 |
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations PK Brastianos, PM Horowitz, S Santagata, RT Jones, A McKenna, G Getz, ... Nature genetics 45 (3), 285-289, 2013 | 676 | 2013 |
Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective … A Pastore, V Jurinovic, R Kridel, E Hoster, AM Staiger, M Szczepanowski, ... The lancet oncology 16 (9), 1111-1122, 2015 | 631 | 2015 |
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing N Wagle, MF Berger, MJ Davis, B Blumenstiel, M DeFelice, P Pochanard, ... Cancer discovery 2 (1), 82-93, 2012 | 622 | 2012 |
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing N Wagle, MF Berger, MJ Davis, B Blumenstiel, M DeFelice, P Pochanard, ... Cancer discovery 2 (1), 82-93, 2012 | 622 | 2012 |
Targetable genetic features of primary testicular and primary central nervous system lymphomas B Chapuy, MGM Roemer, C Stewart, Y Tan, RP Abo, L Zhang, AJ Dunford, ... Blood, The Journal of the American Society of Hematology 127 (7), 869-881, 2016 | 517 | 2016 |
Validation of OncoPanel: a targeted next-generation sequencing assay for the detection of somatic variants in cancer EP Garcia, A Minkovsky, Y Jia, MD Ducar, P Shivdasani, X Gong, ... Archives of Pathology and Laboratory Medicine 141 (6), 751-758, 2017 | 388 | 2017 |
Institutional implementation of clinical tumor profiling on an unselected cancer population LM Sholl, K Do, P Shivdasani, E Cerami, AM Dubuc, FC Kuo, EP Garcia, ... JCI insight 1 (19), 2016 | 378 | 2016 |
Novel peptide inhibitors of angiotensin-converting enzyme 2 L Huang, DJ Sexton, K Skogerson, M Devlin, R Smith, I Sanyal, T Parry, ... Journal of Biological Chemistry 278 (18), 15532-15540, 2003 | 287 | 2003 |
Genomic heterogeneity as a barrier to precision medicine in gastroesophageal adenocarcinoma E Pectasides, MD Stachler, S Derks, Y Liu, S Maron, M Islam, L Alpert, ... Cancer discovery 8 (1), 37-48, 2018 | 273 | 2018 |
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism P Bandopadhayay, LA Ramkissoon, P Jain, G Bergthold, J Wala, R Zeid, ... Nature genetics 48 (3), 273-282, 2016 | 269 | 2016 |
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1 LA Ramkissoon, PM Horowitz, JM Craig, SH Ramkissoon, BE Rich, ... Proceedings of the National Academy of Sciences 110 (20), 8188-8193, 2013 | 229 | 2013 |
MAP2K1 and MAP3K1 mutations in langerhans cell histiocytosis DS Nelson, A van Halteren, WT Quispel, C van den Bos, JVMG Bovee, ... Genes, Chromosomes and Cancer 54 (6), 361-368, 2015 | 197 | 2015 |
Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer MB Yurgelun, AB Chittenden, V Morales-Oyarvide, DA Rubinson, ... Genetics in Medicine 21 (1), 213-223, 2019 | 186 | 2019 |
Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing LE MacConaill, RT Burns, A Nag, HA Coleman, MK Slevin, K Giorda, ... BMC genomics 19, 1-10, 2018 | 186 | 2018 |
The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine A Garofalo, L Sholl, B Reardon, A Taylor-Weiner, A Amin-Mansour, ... Genome medicine 8, 1-10, 2016 | 186 | 2016 |
BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers RP Abo, M Ducar, EP Garcia, AR Thorner, V Rojas-Rudilla, L Lin, ... Nucleic acids research 43 (3), e19-e19, 2015 | 186 | 2015 |
Genomic landscape of high-grade meningiomas WL Bi, NF Greenwald, M Abedalthagafi, J Wala, WJ Gibson, PK Agarwalla, ... NPJ genomic medicine 2 (1), 15, 2017 | 184 | 2017 |
Somatic activating ARAF mutations in Langerhans cell histiocytosis DS Nelson, W Quispel, G Badalian-Very, AGS van Halteren, ... Blood, The Journal of the American Society of Hematology 123 (20), 3152-3155, 2014 | 180 | 2014 |