Personal omics profiling reveals dynamic molecular and medical phenotypes R Chen (Co-First), GI Mias, J Li-Pook-Than, L Jiang, HYK Lam, R Chen, ... Cell 148 (6), 1293-1307, 2012 | 1416 | 2012 |
Patient-specific induced pluripotent stem cell as a model for familial dilated cardiomyopathy N Sun, M Yazawa, J Liu, L Han, V Sanchez-Freire, OJ Abilez, ... Science translational medicine 4 (130), 130ra47, 2012 | 797 | 2012 |
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy N Sun, M Yazawa, J Liu, L Han, V Sanchez-Freire, OJ Abilez, ... Science Translational Medicine 4 (130), 130ra47-130ra47, 2012 | 795 | 2012 |
TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer MG Kelly, AB Alvero, R Chen, DA Silasi, VM Abrahams, S Chan, I Visintin, ... Cancer research 66 (7), 3859-3868, 2006 | 659 | 2006 |
Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance AB Alvero, R Chen, HH Fu, M Montagna, PE Schwartz, T Rutherford, ... Cell Cycle 8 (1), 158-166, 2009 | 614 | 2009 |
Performance comparison of exome DNA sequencing technologies MJ Clark, R Chen (Co-First), HYK Lam, KJ Karczewski, R Chen, ... Nature biotechnology 29 (10), 908-914, 2011 | 602 | 2011 |
The Integrative Human Microbiome Project: dynamic analysis of microbiome-host omics profiles during periods of human health and disease. HMP Integrative Cell host & microbe 16 (3), 276, 2014 | 523 | 2014 |
Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells R Chen, AB Alvero, DA Silasi, MG Kelly, S Fest, I Visintin, A Leiser, ... Oncogene 27 (34), 4712-4723, 2008 | 377 | 2008 |
Promise of personalized omics to precision medicine R Chen, M Snyder Wiley Interdisciplinary Reviews: Systems Biology and Medicine 5 (1), 73-82, 2013 | 369 | 2013 |
Performance comparison of whole-genome sequencing platforms HYK Lam, MJ Clark, R Chen, R Chen, G Natsoulis, M O'Huallachain, ... Nature biotechnology 30 (1), 78-82, 2012 | 368 | 2012 |
The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome YK Paik, SK Jeong, GS Omenn, M Uhlen, S Hanash, SY Cho, HJ Lee, ... Nature biotechnology 30 (3), 221-223, 2012 | 328 | 2012 |
Trophoblast–macrophage interactions: a regulatory network for the protection of pregnancy S Fest, PB Aldo, VM Abrahams, I Visintin, A Alvero, R Chen, SL Chavez, ... American Journal of Reproductive Immunology 57 (1), 55-66, 2007 | 309 | 2007 |
Cancers take their Toll—the function and regulation of Toll-like receptors in cancer cells R Chen, AB Alvero, DA Silasi, KD Steffensen, G Mor Oncogene 27 (2), 225-233, 2008 | 274 | 2008 |
Small-magnitude effect sizes in epigenetic end points are important in children’s environmental health studies: the Children’s Environmental Health and Disease Prevention … CV Breton, CJ Marsit, E Faustman, K Nadeau, JM Goodrich, DC Dolinoy, ... Environmental health perspectives 125 (4), 511-526, 2017 | 266 | 2017 |
TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214 G Yin, R Chen (Co-First), AB Alvero, HH Fu, J Holmberg, C Glackin, ... Oncogene 29 (24), 3545-3553, 2010 | 264 | 2010 |
Inflammation, Cancer and Chemoresistance: Taking Advantage of the Toll‐Like Receptor Signaling Pathway R Chen, AB Alvero, DA Silasi, G Mor American Journal of Reproductive Immunology 57 (2), 93-107, 2007 | 237 | 2007 |
Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway (vol 111, pg 236, 2014) GM Enns, V Shashi, M Bainbridge, MJ Gambello, FR Zahir, T Bast, ... GENETICS IN MEDICINE 16 (7), 568-568, 2014 | 236* | 2014 |
Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway GM Enns, V Shashi, M Bainbridge, MJ Gambello, FR Zahir, T Bast, ... Genetics in Medicine 16 (10), 751-758, 2014 | 236 | 2014 |
Whole-genome haplotyping using long reads and statistical methods V Kuleshov, D Xie, R Chen (Co-First), D Pushkarev, Z Ma, T Blauwkamp, ... Nature biotechnology 32 (3), 261, 2014 | 228 | 2014 |
Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias R Chen (Co-First), S Giliani, G Lanzi, GI Mias, S Lonardi, K Dobbs, ... Journal of Allergy and Clinical Immunology 132 (3), 656-664. e17, 2013 | 166 | 2013 |