| Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life CA Finlay, PW Hinds, TH Tan, D Eliyahu, M Oren, AJ Levine Molecular and Cellular Biology 8 (2), 531-539, 1988 | 1488 | 1988 |
| The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation: duration of JNK activation may determine cell death and proliferation YR Chen, X Wang, D Templeton, RJ Davis, TH Tan Journal of Biological Chemistry 271 (50), 31929-31936, 1996 | 1124 | 1996 |
| Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in γ radiation-induced apoptosis YR Chen, CF Meyer, TH Tan Journal of Biological Chemistry 271 (2), 631-634, 1996 | 580 | 1996 |
| Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin YR Chen, TH Tan Oncogene 17 (2), 173-178, 1998 | 513 | 1998 |
| Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism R Yu, C Chen, YY Mo, V Hebbar, ED Owuor, TH Tan, ANT Kong Journal of Biological Chemistry 275 (51), 39907-39913, 2000 | 415 | 2000 |
| Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product S Ruben, H Poteat, TH Tan, K Kawakami, R Roeder, W Haseltine, ... Science 241 (4861), 89-92, 1988 | 351 | 1988 |
| The c-Jun N-terminal kinase pathway and apoptotic signaling YR Chen, TH Tan International Journal of Oncology 16 (4), 651-713, 2000 | 317 | 2000 |
| Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates YR Chen, W Wang, ANT Kong, TH Tan Journal of Biological Chemistry 273 (3), 1769-1775, 1998 | 307 | 1998 |
| DUSPs, to MAP kinases and beyond CY Huang, TH Tan Cell & Bioscience 2 (1), 1-10, 2012 | 305 | 2012 |
| Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade. MC Hu, WR Qiu, X Wang, CF Meyer, TH Tan Genes & Development 10 (18), 2251-2264, 1996 | 298 | 1996 |
| Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4 X Zhang, Y Ozawa, H Lee, YD Wen, TH Tan, BE Wadzinski, E Seto Genes & Development 19 (7), 827-839, 2005 | 290 | 2005 |
| Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells S Mandlekar, R Yu, TH Tan, ANT Kong Cancer Research 60 (21), 5995-6000, 2000 | 273 | 2000 |
| The interleukin 2 CD28-responsive complex contains at least three members of the NF-κB family: c-Rel, p50, and p65. P Ghosh, TH Tan, NR Rice, A Sica, HA Young Proceedings of the National Academy of Sciences, USA 90 (5), 1696-1700, 1993 | 263 | 1993 |
| Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor β (TGF-β)-activated … W Wang, G Zhou, MCT Hu, Z Yao, TH Tan Journal of Biological Chemistry 272 (36), 22771-22775, 1997 | 254 | 1997 |
| Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion HS Yang, CP Matthews, T Clair, Q Wang, AR Baker, CCH Li, TH Tan, ... Molecular and Cellular Biology 26 (4), 1297-1306, 2006 | 240 | 2006 |
| p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens R Yu, S Mandlekar, W Lei, WE Fahl, TH Tan, ANT Kong Journal of Biological Chemistry 275 (4), 2322-2327, 2000 | 238 | 2000 |
| Activation of mitogen-activated protein kinases by green tea polyphenols: potential signaling pathways in the regulation of antioxidant-responsive element-mediated phase II … R Yu, JJ Jiao, JL Duh, K Gudehithlu, TH Tan, AN Kong Carcinogenesis 18 (2), 451-456, 1997 | 228 | 1997 |
| A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway Z Yao, G Zhou, XS Wang, A Brown, K Diener, H Gan, TH Tan Journal of Biological Chemistry 274 (4), 2118-2125, 1999 | 221 | 1999 |
| Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex TH Tan, J Wallis, AJ Levine Journal of virology 59 (3), 574-583, 1986 | 201 | 1986 |
| Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase SW Xuhong, K Diener, D Jannuzzi, D Trollinger, T Tse-Hua, H Lichenstein, ... Journal of Biological Chemistry 271 (49), 31607-31611, 1996 | 199 | 1996 |
